Results 81 to 90 of about 28,155 (267)

TEMPORALIDADES JESUITAS, CAPITALES Y CRÉDITO EN EL BUENOS AIRES TARDÍO COLONIAL (1767-1813)

Revista de Historia Americana y Argentina, 2018
Numerosas investigaciones interesadas en el proceso desvinculador iniciado por el reformismo borbónico, han estudiado la administración laica del patrimonio jesuita incautado en diversas regiones hispanoamericanas.
María Valeria Ciliberto
doaj  

Detection of KPC-producing Enterobacterales species in wastewater samples from the Gran Concepción Metropolitan area, Chile

Biological Research
Background Carbapenemase-mediated resistance to carbapenems is a significant public health concern due to its potential for widespread dissemination.
Franco Ilabaca-Carrasco, Carlos Peña-Raddatz, Claudia Torres-Bustos, Mauricio Hernández-Cea, Guillermo Nourdin-Galindo, Pablo Saldivia-Flandez, Cristian Vargas, Elard Koch, Helia Bello-Toledo, Gerardo González-Rocha, Andrés Opazo-Capurro   +10 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Las ciencias sociales y los dispositivos de la complejidad

Cuadernos de Administración, 2013
Se presenta una perspectiva de comparación entre los métodos cualitativos y cuantitativos tradicionales de la investigación y las potencialidades del nuevo paradigma del modelamiento y simulación para la investigación en ciencias sociales, sus diferentes
Rodrigo Martínez Díaz, Álvaro Zapata Domínguez   +1 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Social Agentics

Companion Publication of the 2025 Conference on Computer-Supported Cooperative Work and Social Computing
Agentic AI is being heralded as the next step in the development of AI systems. Agentics, complex ensembles of different machine learning, data processing, and generative AI models, can provide new autonomous and proactive decision-making capabilities to organizations, participate in complex workflows, and, when needed, seek guidance from and provide ...
Matt Ratto, Anastasia Kuzminykh, Shion Guha, Edith Law, John Vines   +4 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source