Results 91 to 100 of about 109,705 (362)
Distribution of Glycoconjugates in the Gills of Oscar Fish (Astronotus ocellatus)
Glycoconjugates involved in many functions are produced by many cell types. This study aimed to investigate the glycoconjugate expression in the Oscar fish (Astronotus ocellatus) gills using five horseradish peroxidase-conjugated lectins.
Mustafa Öztop+2 more
doaj +1 more source
Alterations in Lectin Binding to the Epidermis Following Treatment with 8-Methoxypsoralen Plus Long-Wave Ultraviolet Radiation [PDF]
The alterations in lectin fluorescence stainings to the epidermis were examined in guinea pig skin treated with topical application of a 1% 8-methoxypsoralen (8MOP) solution plus long-wave ultraviolet (UVA) radiation (1.5–3.5 J/cm2) (PUVA). Serial biopsy
Danno, Kiichiro+2 more
core +1 more source
Structural basis of multivalent binding to wheat germ agglutinin.
The inhibition of carbohydrate-protein interactions by tailored multivalent ligands is a powerful strategy for the treatment of many human diseases. Crucial for the success of this approach is an understanding of the molecular mechanisms as to how a ...
D. Schwefel+7 more
semanticscholar +1 more source
Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser+20 more
wiley +1 more source
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang+12 more
wiley +1 more source
The objective of this study was to identify the type of specific glycoconjugates and its distribution in testicular spermatogenic cells in muntjak (Muntiacus muntjak muntjak) based on lectins histochemistry.
Sri Wahyuni+9 more
doaj +1 more source
A novel method for negating cold agglutination interference by dithiothreitol during complete blood count and peripheral blood smear: a case study [PDF]
Cold agglutinin disease is an autoimmune disorder that is characterized by antibodies attacking polysaccharide antigens on one’s own erythrocytes.
Hamit Yasar Ellidag+2 more
doaj +1 more source
Pathways of trunk neural crest cell migration in the mouse embryo as revealed by vital dye labelling [PDF]
Analysis of neural crest cell migration in the mouse has been difficult due to the lack of reliable cell markers. Recently, we found that injection of DiI into the chick neural tube marks premigratory neural crest cells whose endfeet are in contact with ...
Bronner-Fraser, Marianne E.+2 more
core
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song+17 more
wiley +1 more source
Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan+10 more
wiley +1 more source