Results 131 to 140 of about 53,061 (292)

Impact of Prior Treatment History on Recurrence After Complete Response to Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Aim Integration of locoregional treatments (LRTs) with atezolizumab plus bevacizumab (atezo/bev) has improved treatment outcomes, enabling an increasing number of patients with unresectable hepatocellular carcinoma (HCC) to achieve a complete response (CR). A comprehensive analysis of recurrence following CR may provide insights into prognosis.
Tasuku Nakabori   +11 more
wiley   +1 more source

Ruxolitinib Suppresses Interferon‐γ‐Induced JAK/STAT Activation in Oral Keratinocytes

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives The Janus kinase (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway plays a crucial role in oral inflammatory diseases such as oral lichen planus (OLP) and periodontitis. Interferon‐gamma (IFN‐γ) is a cytokine that activates the JAK/STAT pathway.
Kim N. Stolte   +4 more
wiley   +1 more source

Generation of Mice Harboring Bicc1 Conditional Null Alleles

open access: yesgenesis, Volume 64, Issue 1, February 2026.
ABSTRACT Bicaudal C1 (Bicc1) encodes an RNA‐binding protein critical for many organ development and epithelial tissue homeostasis. Bicc1 null mutations have been shown to lead to the development of polycystic kidney disease (PKD) and death at an early prenatal stage.
Chia‐Feng Liu   +4 more
wiley   +1 more source

Uncovering the Key Factors Influencing Phytochemical and Phytopharmacological Properties During Medicinal Plant Processing

open access: yeseFood, Volume 7, Issue 1, February 2026.
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley   +1 more source

Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications

open access: yeseFood, Volume 7, Issue 1, February 2026.
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza   +13 more
wiley   +1 more source

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