Results 131 to 140 of about 109,705 (362)
ESC Heart Failure, EarlyView.Abstract Aims Right ventricular (RV) remodelling, a progressive condition characterized by maladaptive cardiac structural and functional changes, primarily results from prolonged pressure overload in patients with pulmonary hypertension (PH). Accurate, universal and easy‐to‐use biomarkers for assessing the severity of RV remodelling are lacking.
Xuenan Wang +5 more
wiley +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome accounting for half of heart failure cases. Although natriuretic peptides are the most accepted and extensively used biomarkers for heart failure, their diagnostic accuracy for HFpEF remains debatable.
Reza Parvan +8 more
wiley +1 more source
Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy [PDF]
, 2014 Chronic neurohormonal and mechanical stresses are central fea-tures of heart disease. Increasing evidence supports a role forthe transient receptor potential canonical channels TRPC3 andTRPC6 in this pathophysiology.
Andersen, Asger +13 more
core +1 more source
Cell Structure and Function, 1981 The effects of lectins on hydra (Hydra japonica) were investi-gated in order to clarify the mechanics of its feeding response. Concanavalin agglutinin (Con A) induced rapid and prolonged tentacle contractions, but did not induce marked contractions of the body column.
Taira Enomoto +3 more
openaire +3 more sources
European Journal of Heart Failure, EarlyView.Myocardial ketone body oxidation contributes to empagliflozin‐induced improvements in cardiac contractility. Abstract Aims Sodium–glucose cotransporter 2 inhibitors (SGLT2i) improve cardiac performance and clinical outcomes in patients with heart failure, yet mechanisms underlying these beneficial effects remain incompletely understood.
Suzanne Nathalie Voorrips +11 more
wiley +1 more source
Study of plant lectins anti-tumor action on glioma cells of different stages of anaplasia
Ukrainian Neurosurgical Journal, 2009 A direct cytotoxity effect of lectins: soybean (SBA), laburnum anagyroides agglutinin (LABA), peanut agglutinin (PNA), wheat germ agglutinin (WGA), lentil lectin (LCL), mistletoe lectin (Mil) on the glioma cells of different stages of ...
N. I. Lisyany +6 more
doaj +1 more source
Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation [PDF]
, 2017 ACKNOWLEDGMENTS We acknowledge Jennifer Lodge, Woei Lam, and Rajendra Upadhya for developing and sharing the chitin and chitosan MTBH assay. We thank Todd Brennan of Duke University for providing MyD88-deficient mice.
Carol Munro +8 more
core +3 more sources
Induction of IL 2 receptor expression and cytotoxicity of thymocytes by stimulation with TCF1 [PDF]
, 1985 We investigated the role of T cell cytotoxicity inducing factor 1 (TCF1) in the induction of a cytotoxic T cell response. We found that help-deficient thymocyte cultures supplied with saturating amounts of purified IL 2 did not develop CTL in a 5-day ...
Diamantstein, T. +6 more
core
FGB1 and WSC3 are in planta-induced beta-glucan-binding fungal lectins with different functions
, 2019 In the root endophyte Serendipita indica, several lectin-like members of the expanded multigene family of WSC proteins are transcriptionally induced in planta and are potentially involved in beta-glucan remodeling at the fungal cell wall.
Becker, S. +8 more
core +1 more source
International Journal of Cancer, EarlyView.What's New? Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.
Irene van der Haar Àvila +11 more
wiley +1 more source