Results 71 to 80 of about 18,578 (279)

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely   +14 more
wiley   +1 more source

Identification of serum C4BPA as a potential diagnostic marker of right ventricular remodelling via proteomic analysis

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Right ventricular (RV) remodelling, a progressive condition characterized by maladaptive cardiac structural and functional changes, primarily results from prolonged pressure overload in patients with pulmonary hypertension (PH). Accurate, universal and easy‐to‐use biomarkers for assessing the severity of RV remodelling are lacking.
Xuenan Wang   +5 more
wiley   +1 more source

Rapid Contraction of Hydra Tentacles Caused by Concanavalin Agglutinin, Lotus tetragonolobus Agglutinin and Ulex europeus Agglutinin

open access: yesCell Structure and Function, 1981
The effects of lectins on hydra (Hydra japonica) were investi-gated in order to clarify the mechanics of its feeding response. Concanavalin agglutinin (Con A) induced rapid and prolonged tentacle contractions, but did not induce marked contractions of the body column.
Taira Enomoto   +3 more
openaire   +3 more sources

Multi‐microRNA diagnostic panel for heart failure with preserved ejection fraction in preclinical and clinical settings

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome accounting for half of heart failure cases. Although natriuretic peptides are the most accepted and extensively used biomarkers for heart failure, their diagnostic accuracy for HFpEF remains debatable.
Reza Parvan   +8 more
wiley   +1 more source

Myocardial ketone body oxidation contributes to empagliflozin‐induced improvements in cardiac contractility in murine heart failure

open access: yesEuropean Journal of Heart Failure, EarlyView.
Myocardial ketone body oxidation contributes to empagliflozin‐induced improvements in cardiac contractility. Abstract Aims Sodium–glucose cotransporter 2 inhibitors (SGLT2i) improve cardiac performance and clinical outcomes in patients with heart failure, yet mechanisms underlying these beneficial effects remain incompletely understood.
Suzanne Nathalie Voorrips   +11 more
wiley   +1 more source

Prevalence and Antibiotic Susceptibility Pattern of Salmonella Enterica Isolated from Apparently Healthy Students Screened for Salmonella Agglutinins

open access: yesSokoto Journal of Medical Laboratory Science, 2022
Infections caused by Salmonella enterica remains a major public health concern worldwide, contributing to the economic burden of both industrialized and underdeveloped countries through the costs associated with surveillance, prevention and treatment of ...
Musa Yakubu Tula*1, Zulkifli Muhammed Usman 3, Zainab Mohammed Chiroma 1, Richard Elisha 2, Evangeline Ogonna Okpalauwaekwe 1, and Mary Ngozi Ogu 1
doaj  

THE PERSISTENCE OF LEPTOSPIRAL AGGLUTININS TITERS IN HUMAN SERA DIAGNOSED BY THE MICROSCOPIC AGGLUTINATION TEST

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1998
The persistence of agglutinins detected by MAT has created some problems to the interpretation of the results. The aim of this study was to examine the data of serology from 70 patients with serologically confirmed diagnosis of leptospirosis by during 3 ...
Eliete C. ROMERO   +2 more
doaj   +1 more source

Tumor desialylation surpasses anti‐PD‐L1 checkpoint therapy in restoring anti‐tumor immunity in a murine model for colorectal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.
Irene van der Haar Àvila   +11 more
wiley   +1 more source

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