Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Behaviour of cement composites with lightweight and heavyweight aggregates at high temperatures
, 2016 Lenka Bodnárová +4 more
openalex +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Effect of Basalt Fibers on the Performance of CO2-Cured Recycled Aggregate Concrete Composite Slab–Column Assemblies with Bolted Connections Under NaCl Erosion [PDF]
Di Wang +7 more
openalex +1 more source
Application of functionally graded materials for severe plastic deformation and smart materials: experimental study and finite element analysis [PDF]
, 2012 Functionally graded materials (FGMs) refer to the composite materials where the compositions or the microstructures are locally varied so that a certain variation of the local material properties is achieved.
Jamian, Saifulnizan
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Cracking risk of high-performance cement composites due to restrained autogenous shrinkage with and without soaked lightweight aggregate [PDF]
, 2023 A. Zieliński +2 more
openalex +1 more source
Mission Impossible!? On the Harmonization of National Allocation Plans under the EU Emissions Trading Directive [PDF]
Starting in 2005, the EU will implement a CO2 emissions trading scheme. In this paper we show that the outspoken goals of economic efficiency and free allocation of allowances are incompatible with harmonized allocation rules.
Böhringer, Christoph, Lange, Andreas
core
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source