Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The Variances of Regression Coefficient Estimates Using Aggregate Data [PDF]
This paper considers the effect of aggregation on the variance of parameter estimates for a linear regression model with random coefficients and an additive error term.
Roy E. Welsch, Edwin Kuh
core
Data set for journal paper "Chemical aspects related to using recycled geopolymers as an aggregate"
All data used to produce the graphs included in the journal paper "Chemical aspects related to using recycled geopolymers as an aggregate" published in "Advances in Cement Research".All information required to interpret the data are in the associated ...
Chaliasou, Anna
core +1 more source
Selective aggregation scheme for multi-dimensional data with type-based verification
With the rapid proliferation of the Internet of things (IoT), ciphertext data aggregation has emerged as a fundamental technique to enhance transmission efficiency while preserving data privacy.
NIU Kun +4 more
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Aggregate Representations of Aggregate Games [PDF]
An aggregate game is a normal-form game with the property that each player’s payoff is a function only of his own strategy and an aggregate function of the strategy profile of all players. Aggregate games possess a set of purely algebraic properties that
Stole, Lars, Martimort, David
core
Prone Positioning in Patients With COVID-19: Analysis of Multicenter Registry Data and Meta-analysis of Aggregate Data. [PDF]
Kollias A +7 more
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Individual participant data meta-analysis versus aggregate data meta-analysis: A case study in eczema and food allergy prevention. [PDF]
Van Vogt E +7 more
europepmc +1 more source

