Results 131 to 140 of about 1,654,624 (346)

A framework for prospective, adaptive meta-analysis (FAME) of aggregate data from randomised trials. [PDF]

open access: yesPLoS Med, 2021
Tierney JF   +8 more
europepmc   +1 more source

Lumpy Investment in Dynamic General Equilibrium [PDF]

open access: yes
Microeconomic lumpiness matters for macroeconomics. According to our DSGE model, it is responsible for 92 percent of the smoothing in the investment response to aggregate shocks, and it introduces important nonlinearities and history dependance in ...
Eduardo Engel   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Occurrence cubes: a new paradigm for aggregating species occurrence data

open access: green, 2020
Damiano Oldoni   +7 more
openalex   +1 more source

Heterogeneous Productivity Shocks, Elasticity of Substitution and Aggregate Fluctuations [PDF]

open access: yes
We use a Dixit-Stiglitz setting to show that aggregate productivity fluctuations can be generated through changes in the dispersion of firms' productivity.
Alessio, Moro, Rodolfo, Stucchi
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Selective aggregation scheme for multi-dimensional data with type-based verification

open access: yesTongxin xuebao
With the rapid proliferation of the Internet of things (IoT), ciphertext data aggregation has emerged as a fundamental technique to enhance transmission efficiency while preserving data privacy.
NIU Kun   +4 more
doaj  

A comparative study of symbolic aggregate approximation and topological data analysis

open access: yesQuantitative Finance and Economics
The movement of stocks is often perceived as random due to the complex interactions between different stocks and the inherently chaotic nature of the market.
Fredrik Hobbelhagen, Ioannis Diamantis
doaj   +1 more source

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