FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Prediction of Lifespan of Railway Ballast Aggregate According to Mechanical Properties of it
The Baltic Journal of Road and Bridge Engineering, 2017 As the railway lifespan is the main criterion for selection of the aggregate for ballast and for planning the maintenance of the railroad, it is important to define the relationship between the particle load resistant characteristics and a lifetime of ...
Vaidas Ramūnas +4 more
doaj +1 more source
The contribution of ecological footprinting to planning policy development: using REAP to evaluate policies for sustainable housing construction [PDF]
, 2008 The complexity of the sustainable-development policy goal is such that policy makers are searching for tools to enable them to evaluate and develop policy directions.
Nye, M, Rydin, Y
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Algorithms of capacity balancing of printing machineries for Alfa Foils, a.s. planning system [PDF]
Acta Montanistica Slovaca, 2009 Basic absence for orders income is not definning of rules for their evaluation. It is very important todefine necessary rules and define competence of each workers, that influence production planning, itmeans to define competence of planning workers and ...
Martin Straka, Dušan Malindžák
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Algorithms of capacity planning and production scheduling prognosis creation a capacity balance of Alfa Foils, a.s. planning system [PDF]
Acta Montanistica Slovaca, 2008 Firm forecasting and planning base on operative approach bears only measure of request production saturation. After overload“point of bearing” occur collapse planning system, i.e.
Zuzana Marková +2 more
doaj
Hatékonyság növelése tervezéssel - avagy: aggregált tervezés alkalmazása egy magyar vállalatnál = Improving efficiency with production planning - Applying aggregate planning at a Hungarian company [PDF]
, 2009 A cikk alapvető kérdése, hogy miképpen használható a tervezés a termelési folyamatok, s ezzel a vállalati m}uködés egészének hatékonyságnövelése érdekében.
Dobos, Imre +2 more
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
AN INTERACTIVE PROCEDURE FOR AGGREGATE PRODUCTION PLANNING
Croatian Operational Research Review, 2013 Minimizing production cost over the planning period is usually assumed to be the objective of aggregate planning. However, other issues of strategic type may be even more important.
Maciej Nowak
doaj