Results 41 to 50 of about 4,400 (214)

Maritime Inventory Routing for LNG Distribution from an FSRU Under Carbon Tax: A Column Generation Approach with a Diving Heuristic

Systems
A floating storage and regasification unit (FSRU) provides flexible infrastructure for liquefied natural gas (LNG) import, storage, regasification, and regional distribution.
Kanietova Aiymbubu, Kang Chen, Xiaoya An, Xu Xin, Jichun Li, Haiyan Dai, Chunliang Liu   +6 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Analisis Sistem Rantai Pasok Pt. Semen Gresik (Persero) Tbk

Jurnal Optimasi Sistem Industri, 2011
The cement industry is an industry that requires a supply chain system is structured and well organized, it is influenced by several things, namely the level of demand for raw materials (raw material), resources, production processes, scheduling ...
Bahrain Boru Sinaga, Gema Alif Utama, Hesti Rafianti, Kushisa Atta Jaeba, Wiwit Afrigus   +4 more
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Interfaz entre el plan de producción y el programa de producción en ambientes de ensamble Interface between the production plan and the master production schedule in assembly environments

Tecnología en Marcha, 2012
En un entorno de producción existe una relación directa entre el mercado y los procesos de manufactura de los bienes. Sin embargo, cuando la producción está inmersa en un ambiente de ensamble, el procedimiento de la planificación y la programación se ...
Marcos Moya Navarro, Magaly Sánchez Brenes   +1 more
doaj  

EVHF-GCN: An Emergency Vehicle Priority Scheduling Model Based on Heterogeneous Feature Fusion With Graph Convolutional Networks

IEEE Access
Traffic flow prediction is a crucial aspect of Intelligent Transport Systems, offering a scientific foundation for urban transport system management and planning.
Jianxin Feng, Guanlin Guo, Jiahao Wang, Xiaoyao Liu, Zhiguo Liu, Yuanming Ding   +5 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Toward Trustworthy AI Software Evaluation: A Controlled Benchmark of Deep Learning Architectures for 24-h Photovoltaic Power Forecasting

Computers
Accurate 24 h photovoltaic (PV) power forecasting is essential for day-ahead scheduling, storage operation, reserve planning, and market participation.
Husein Mauladdawilah, Mohammed Balfaqih, Zain Balfagih, Aimad El Habti, María del Carmen Pegalajar, Eulalia Jadraque Gago   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Novel Fuzzy Multi-Criteria Decision Framework for Maritime Infrastructure Maintenance

Infrastructures
The maintenance of critical maritime infrastructure is essential for ensuring the safe, reliable, and efficient operations of marine seaports. This paper proposes a novel fuzzy multi-criteria decision framework for evaluating the maintenance practices ...
Ehidiame Ibazebo, Vimal Savsani, Arti Siddhpura, Milind Siddhpura, Poonam Savsani   +4 more
doaj   +1 more source