Results 121 to 130 of about 27,398 (275)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Cryptanalysis and improvement of certificateless aggregate signature with conditional privacy-preserving for vehicular sensor networks [PDF]
, 2016 Secure aggregate signature schemes have attracted more concern due to their wide application in resource constrained environment. Recently, Horng et al. [S. J.
Hong Yuan, Jiguo Li, Yichen Zhang
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
An Efficient and Secure Certificateless Aggregate Signature From Bilinear Maps
, 2019 Certificateless signature schemes are a very intriguing aspect in information security because of its capability of removing the well-known key escrow problem predominately in ID-based cryptography. He et al.
Sharma, Gaurav +8 more
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Data fusion protocol with source security for sensor networks
Tongxin xuebao, 2010 For the source security need,a digital signature scheme with aggregate signatures,data fusion and batch verification was proposed.Based on the proposed signature scheme and the homomorphic encryption technology,a data fusion protocol with secure sources ...
ZHANG Peng, YU Jian-ping, LIU Hong-wei
doaj +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A new aggregate signature scheme for secure data verification in WSN [PDF]
, 2018 We prepare an ID-based aggregate signature system for WSNs, which can compress many signatures generated by sensor nodes into a short one, i.e., it can reduce the communication and storage cost.
Vinodkumar, P, Srinivas, S
core