Results 71 to 80 of about 197,054 (272)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Efficient and provably-secure certificateless sequential aggregate signature scheme

Tongxin xuebao, 2022
Aiming at the problem that current schemes mostly let the latter signer to verify the multiple signatures of the previous signer, and the message is signed and then passed to the next signer, leading to the efficiency problem of long overall signature ...
Zhu WANG, Siqi YANG, Fenghua LI, Kui GENG, Tingting PENG, Mengyao SHI   +5 more
doaj   +2 more sources

Certificateless Anonymous Authentication Scheme Supporting Illegal Signatures Localization for Internet of Vehicles [PDF]

Jisuanji gongcheng
In the Internet of Vehicles (IoV) environment, vehicles are connected to public networks through the Internet and information is vulnerable to various malicious attacks from attackers during transmission.
YANG Xiaodong, LI Muzi, MA Guozu, LI Songyu, WANG Caifen
doaj   +1 more source

Privacy-preserving data aggregation in resource-constrained sensor nodes in Internet of Things: A review

, 2018
Privacy problems are lethal and getting more attention than any other issue with the notion of the Internet of Things (IoT). Since IoT has many application areas including smart home, smart grids, smart healthcare system, smart and intelligent ...
Ali, Inayat, Khan, Eraj, Sabir, Sonia
core   +2 more sources

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Cremonian Space-Time(s) as an Emergent Phenomenon

, 2004
It is shown that the notion of fundamental elements can be extended to_any_, i.e. not necessarily homaloidal, web of rational surfaces in a three-dimensional projective space.
Saniga, Metod
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A Certificateless Aggregate Arbitrated Signature Scheme for IoT Environments

Sensors, 2020
The Internet of Things (IoT) environment consists of numerous devices. In general, IoT devices communicate with each other to exchange data, or connect to the Internet through a gateway to provide IoT services.
Dae-Hwi Lee, Kangbin Yim, Im-Yeong Lee
doaj   +1 more source