Results 71 to 80 of about 26,610 (245)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
An improved pairing-free certificateless aggregate signature scheme for healthcare wireless medical sensor networks. [PDF]
PLoS One, 2022 Zhou L, Yin X.
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Individual health passport storage, sharing and verification scheme based on blockchain
网络与信息安全学报As the demand for international travel escalates, the individual health passport has emerged as an essential instrument for verifying the health status of travelers and fulfilling entry criteria.
GAO Hancheng +3 more
doaj +3 more sources
MDBV: Monitoring Data Batch Verification for Survivability of Internet of Vehicles
IEEE Access, 2018 Along with the development of vehicular sensors and wireless communication technology, Internet of Vehicles (IoV) is emerging that can improve traffic efficiency and provide a comfortable driving environment.
Jingwei Liu +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
New certificateless aggregate signature scheme with universal designated verifier
Tongxin xuebao, 2017 Certificateless aggregate signature(CLAS) schemes with universal designated verifier had been widely applied in resource-constrained wireless mobile networks,because they could not only solve the problems of the certificate management and private key ...
Zhi-yan XU +3 more
doaj +2 more sources
Signature of an aggregation-prone conformation of tau
Scientific Reports, 2017 AbstractThe self-assembly of the microtubule associated tau protein into fibrillar cell inclusions is linked to a number of devastating neurodegenerative disorders collectively known as tauopathies. The mechanism by which tau self-assembles into pathological entities is a matter of much debate, largely due to the lack of direct experimental insights ...
Eschmann, Neil +8 more
openaire +5 more sources