Results 71 to 80 of about 198,045 (271)

Boundary drive induced formation of aggregate condensates in stochastic transport with short-range interactions

open access: yes, 2015
We discuss the effects of particle exchange through open boundaries and the induced drive on the phase structure and condensation phenomena of a stochastic transport process with tunable short-range interactions featuring pair-factorized steady states ...
Janke, Wolfhard   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Aggregatable Certificateless Designated Verifier Signature

open access: yesIEEE Access, 2020
In recent years, the Internet of Things (IoT) devices have become increasingly deployed in many industries and generated a large amount of data that needs to be processed in a timely and efficient manner.
Pairat Thorncharoensri   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Efficient and provably-secure certificateless sequential aggregate signature scheme

open access: yesTongxin xuebao, 2022
Aiming at the problem that current schemes mostly let the latter signer to verify the multiple signatures of the previous signer, and the message is signed and then passed to the next signer, leading to the efficiency problem of long overall signature ...
Zhu WANG   +5 more
doaj   +2 more sources

Certificateless Anonymous Authentication Scheme Supporting Illegal Signatures Localization for Internet of Vehicles [PDF]

open access: yesJisuanji gongcheng
In the Internet of Vehicles (IoV) environment, vehicles are connected to public networks through the Internet and information is vulnerable to various malicious attacks from attackers during transmission.
YANG Xiaodong, LI Muzi, MA Guozu, LI Songyu, WANG Caifen
doaj   +1 more source

Automatic Unbounded Verification of Alloy Specifications with Prover9 [PDF]

open access: yes, 2012
Alloy is an increasingly popular lightweight specification language based on relational logic. Alloy models can be automatically verified within a bounded scope using off-the-shelf SAT solvers.
Cunha, Alcino, Macedo, Nuno
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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