Results 51 to 60 of about 6,137 (264)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Identity Based Partial Aggregate Signature Scheme Without Pairing [PDF]

, 2011
An identity based signature allows users to sign their documents using their private keys and the signature can be verified by any one, using the identity of the signer and public parameters of the system.
C. Pandu Rangan, J. Shriram, S. Sharmila Deva Selvi, S. Sree Vivek   +3 more
core  

An Efficient Identity-Based Aggregate Signature Scheme

工程科学与技术, 2011
:Security analyses of an ID-based aggregate signature scheme presented by Song, Kim, Lee and Yoon were given in this paper. It is found that the scheme is universally forgeable.
Du Hong-Zhen
doaj  

Cryptanalysis of Two Signature Schemes for IoT-Based Mobile Payments and Healthcare Wireless Medical Sensor Networks

IEEE Access, 2020
Certificateless cryptography does not require any certificate for the public key authentication and users' public keys are transmitted with ciphertext/signatures or by making them available in the IoT-based public directory in a proper way.
Kyung-Ah Shim
doaj   +1 more source

Deterministic Identity Based Signature Scheme and Its Application for Aggregate Signatures [PDF]

, 2012
Since the introduction of identity based cryptography in 1984 by Adi Shamir, several identity based signature schemes were reported. However, there are only two deterministic identity based signature schemes available in the literature and both of them use probabilistic private key generation and uses bilinear pairing.
S. Sharmila Deva Selvi, S. Sree Vivek, C. Pandu Rangan   +2 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cryptanalysis of Compact Certificateless Aggregate Signature Schemes for HWMSNs and VANETs

IEEE Access
Certificateless cryptosystems resolve the critical problems in public-key cryptosystems and identity-based cryptosystems. A certificateless aggregate signature scheme aggregates multiple signatures of multiple signers into a single signature that ...
Kyung-Ah Shim
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source