Results 81 to 90 of about 1,842,514 (258)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Security Analysis of Aggregate signature and Batch verification signature schemes [PDF]
, 2009 An identity based signature scheme allows any pair of users to communicate securely and to verify each others signatures without exchanging public key certificates. An aggregate signature scheme is a digital signature scheme which supports aggregation of
S. Sharmila Deva Selvi +4 more
core +1 more source
An improved pairing-free certificateless aggregate signature scheme for healthcare wireless medical sensor networks. [PDF]
PLoS One, 2022 Zhou L, Yin X.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
IEEE Access, 2019 Wireless sensor network (WSN) can be widely used in the field of health care since it has many advantages, such as low cost, high efficiency, low latency, and so on.
Hongzhen Du, Qiaoyan Wen, Shanshan Zhang
doaj +1 more source
Efficient Certificate-Less Aggregate Signature Scheme with Conditional Privacy-Preservation for Vehicular Ad Hoc Networks Enhanced Smart Grid System. [PDF]
Sensors (Basel), 2021 Vallent TF, Hanyurwimfura D, Mikeka C.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Id-Based Aggregate Signature Scheme and Its Application in Authenticated Routing [PDF]
, 2014 An aggregate signature scheme can aggregate n signatures on n distinct messages from n distinct signers into a single signature．Thus，n verification equations can be reduced to one．So the aggregate signature adapts to Mobile Ad hoc Network (MANET).
Teng, Jikai, Wang, Daxing
core +1 more source