Results 101 to 110 of about 6,137 (264)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
An Efficient Certificateless Aggregate Signature Scheme for Blockchain-Based Medical Cyber Physical Systems. [PDF]
Sensors (Basel), 2020 Shu H +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
A certificateless aggregate signature scheme for security and privacy protection in VANET
, 2023 [[abstract]]In the vehicular ad hoc network, moving vehicles can keep communicating with each other by entering or leaving the network at any time to establish a new connection.
Ca, Eko Fajar;Cahyadi, Eko Fajar;Su, Tzu-Wei;Su, Tzu-Wei;Ya, Chou-Chen;Yang, Chou-Chen;黃明祥;Hwang, Min-Shiang
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Id-Based Aggregate Signature Scheme and Its Application in Authenticated Routing
, 2014 An aggregate signature scheme can aggregate n signatures on n distinct messages from n distinct signers into a single signature．Thus，n verification equations can be reduced to one．So the aggregate signature adapts to Mobile Ad hoc Network (MANET).
Teng, Jikai, Wang, Daxing
core
Cryptanalysis of a Compact Certificateless Aggregate Signature Scheme
, 2020 In this paper, we cryptanalyze a recently proposed compact certificateless aggregate signature scheme (CCLAS) and show that it is in fact insecure against a Type-I attack.
Gwoboa Horng +2 more
core
A Secure Data Transmission Using Efficient Aggregate Signature Scheme to Verify Data in Wireless Sensor N/W [PDF]
, 2018 We stretch an ID-based aggregate signature (IBAS) scheme for WSNs in cluster-based method . The opponent in our refuge model has the competence to presentation any alliance attacks. If an opponent can use some solitary signatures counting invalid ones to
Dinesh Kumar, Ganti +2 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source