Results 161 to 170 of about 134,314 (260)

Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence. [PDF]

ACS Chem Biol, 2019
Ganesh AN, Aman A, Logie J, Barthel BL, Cogan P, Al-Awar R, Koch TH, Shoichet BK, Shoichet MS.   +8 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

<i>Bacillus tropicus</i> YJ33 and <i>Medicago sativa</i> L. Synergistically Enhance Soil Aggregate Stability in Saline-Alkali Environments. [PDF]

Microorganisms
Li J, Che Y, Chen S, Liu M, Diao M, Yang C, Jia W.   +6 more
europepmc   +1 more source

Effects of Biochar Combined with Nitrogen Fertilizer Reduction on Rapeseed Yield and Soil Aggregate Stability in Upland of Purple Soils. [PDF]

Int J Environ Res Public Health, 2019
Tian X, Li Z, Wang L, Wang Y, Li B, Duan M, Liu B.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Glomalin related soil protein, soil aggregate stability and soil aggregate-associated organic carbon under agroforestry practices in southern Ethiopia. [PDF]

BMC Ecol Evol
Masebo N, Birhane E, Takele S, Perez-Sanz A, Lucena JJ, Belay Z, Anjulo A, Yunta F.   +7 more
europepmc   +1 more source

Soil Photosynthetic Microbial Communities Mediate Aggregate Stability: Influence of Cropping Systems and Herbicide Use in an Agricultural Soil. [PDF]

Front Microbiol, 2019
Crouzet O, Consentino L, Pétraud JP, Marrauld C, Aguer JP, Bureau S, Le Bourvellec C, Touloumet L, Bérard A.   +8 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A 2-year pure biochar addition enhances soil carbon sequestration and reduces aggregate stability in understory conditions. [PDF]

Sci Rep
Wei J, Li Y, Li J, Yan W, Yin Q, Jiang H, Li Z, Jiang J, Li Y, Yao Y, Zhang L.   +10 more
europepmc   +1 more source

Effects of Soil Aggregate Stability on Soil Organic Carbon and Nitrogen under Land Use Change in an Erodible Region in Southwest China. [PDF]

Int J Environ Res Public Health, 2019
Liu M, Han G, Zhang Q.
europepmc   +1 more source