Results 81 to 90 of about 144,685 (260)

Evaluation of the Properties of Bituminous Concrete Prepared from Brick-Stone Mix Aggregate

Advances in Materials Science and Engineering, 2016
The paper describes an investigation into mechanical properties of brick-stone bituminous concrete mix. The effect of brick-stone mix on various mechanical properties of the bituminous concrete such as Marshall stability, flow, Marshall Quotient ...
Dipankar Sarkar, Manish Pal, Ashoke K. Sarkar, Umesh Mishra   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Divergent responses of aggregate breakdown by slaking to nitrogen forms in solution for contrasting soil types

Geoderma
Aggregate stability strongly affects many soil processes and is critical to maintain sustainable agriculture. Aggregate breakdown is controlled by the interaction between soil intrinsic properties and solution characteristics.
Xinliang Wu, Chenyu Wang, Chongfa Cai, Sixu Yao, Jinxing Zhou   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Influence of aggregate gradation on hma mixes stability

Romanian Journal of Transport Infrastructure, 2015
The load transfer capacity of pavements is to a great extend influenced by aggregates. About 85% of the total volume of hot mix asphalt (HMA) mixtures consists of aggregates; thus, they are greatly influenced by aggregate properties like angularity ...
Kalaitzaki Elvira, Kollaros George, Athanasopoulou Antonia   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

An energy‐based aggregate stability method is more management‐sensitive than commercial methods in coarse‐textured, subtropical orchard soils

Agricultural & Environmental Letters
Aggregate stability impacts important soil functions, including carbon/water storage and soil structure. Macroaggregate stability tests, using rainfall simulation or wet sieving, are commonly used, but microaggregate stability tests may be more ...
Yaslin N. Gonzalez, Allan R. Bacon, Sarah L. Strauss, Gabriel Maltais‐Landry   +3 more
doaj   +1 more source

Effects of Freeze–Thaw Cycles on Soil Aggregate Stability and Organic Carbon Distribution Under Different Land Uses

Agriculture
Soil aggregates are critical determinants of soil erosion resistance and nutrient retention capacity, while freeze–thaw cycles (FTCs) induce the structural reorganization of soil aggregates, thereby altering soil stability and influencing soil organic ...
Yuting Cheng, Maolin Liu, Yi Zhang, Shuhao Hao, Xiaohu Dang, Ziyang Wang   +5 more
doaj   +1 more source