Results 91 to 100 of about 2,756,148 (249)

On the stability of utilitarian aggregation

open access: yesTheory and Decision
Abstract In the context of aggregating von Neumann-Morgenstern utilities, we show that bounded violations of the Pareto conditions characterize aggregation rules that are approximately utilitarian. When a single utility function is intended to represent the preference judgments of a group of individuals and the Pareto principles are ...
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Land-use shapes the composition and stability of soil water-stable aggregates in a plateau agro-pastoral ecotone [PDF]

open access: yesPeerJ
Background The northeastern Tibetan Plateau is a typical agro-pastoral ecotone that experiences frequent land-use changes. Maintaining stable soil aggregates in this region is key to protecting the environment and supporting food production on the ...
Ling Bai   +10 more
doaj   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Cement-phosphogypsum stabilized aggregate interlocking road base material: preparation, application and environmental impact

open access: yesJournal of Infrastructure Preservation and Resilience
For the extensive and cost-effective utilization of phosphogypsum in highway engineering, a cement-phosphogypsum stabilized coarse aggregate interlocking road base material is developed in this study.
Zhicheng Zhao   +9 more
doaj   +1 more source

Quantifying the contribution of the root system of alpine vegetation in the soil aggregate stability of moraine

open access: yesInternational Soil and Water Conservation Research, 2017
One fifth of the world's population is living in mountains or in their surrounding areas. This anthropogenic pressure continues to grow with the increasing number of settlements, especially in areas connected to touristic activities, such as the Italian ...
Csilla Hudek   +3 more
doaj   +1 more source

Temporal changes in wet aggregate stability [PDF]

open access: yes, 1992
Aggregate stability, a property that influences a soil's erodibility and hydraulic characteristics, has been shown in previous investigations (e.g., Bullock et al., 1988) to vary over time for some northwestern U.S. soils.
Lehrsch, G.A.   +3 more
core  

Short-term dynamics of soil aggregate stability in the field

open access: yes, 2014
Aggregate stability is a key property affecting the movement and storage of water, seedling emergence, and soil sensitivity to erosion. Many studies have shown that aggregate stability changes through time.
Algayer, Baptiste   +2 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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