Results 181 to 190 of about 677,718 (302)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Measuring soil aggregate stability with mobile phones, lessons, challenges, and future work. [PDF]

Sci Rep
Fajardo M, Pino V, Jones E, Morgan C, Stevenson B, Saby N, Lacoste M, McBratney A.   +7 more
europepmc   +1 more source

Decomposition-aggregation stability analysis [PDF]

This report presents the development and description of the decomposition aggregation approach to stability investigations of high dimension mathematical models of dynamic systems.
Cuk, S. M., Siljak, D. D., Weissenberger, S.   +2 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Effects of different intercropping patterns on soil organic carbon content, enzyme activity, and aggregate stability in Apple orchards on the loess Plateau. [PDF]

Sci Rep
Sun W, Zhao M, Dong T, Ma M.
europepmc   +1 more source

Unstable Individual Bids and Stable Market Demand [PDF]

We explore preference stability at the individual and market level. We examine individual bidding behavior among 116 French consumers who participated in experimental auctions conducted seven months apart for five types of fish.
Alfnes, Frode, Rickertsen, Kyrre, Shogren, Jason F.   +2 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Author Correction: Response of soil organic carbon and soil aggregate stability to changes in land use patterns on the Loess Plateau. [PDF]

Sci Rep
Pan Z, Cai X, Bo Y, Guan C, Cai L, Haider FU, Li X, Yu H.   +7 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Changes of soil organic carbon and aggregate stability along elevation gradient in Cunninghamia lanceolata plantations. [PDF]

Sci Rep
Cao X, Xu Y, Wang F, Zhang Z, Xu X.
europepmc   +1 more source