Results 81 to 90 of about 5,001,808 (350)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Quantifying the contribution of the root system of alpine vegetation in the soil aggregate stability of moraine

open access: yesInternational Soil and Water Conservation Research, 2017
One fifth of the world's population is living in mountains or in their surrounding areas. This anthropogenic pressure continues to grow with the increasing number of settlements, especially in areas connected to touristic activities, such as the Italian ...
Csilla Hudek   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Soil Aggregate Stability Under Freeze–Thaw Cycles in Mollisols as Evidenced by 15N Distribution

open access: yesAgronomy
Freeze–thaw cycles (FTCs) influence soil nitrogen (N) dynamics and soil aggregate stability. However, the driving mechanism affecting aggregate stability from the combined perspective of N components and N distribution by 15N tracing technology in both ...
Yao Wang   +6 more
doaj   +1 more source

Evaluation of the Properties of Bituminous Concrete Prepared from Brick-Stone Mix Aggregate

open access: yesAdvances in Materials Science and Engineering, 2016
The paper describes an investigation into mechanical properties of brick-stone bituminous concrete mix. The effect of brick-stone mix on various mechanical properties of the bituminous concrete such as Marshall stability, flow, Marshall Quotient ...
Dipankar Sarkar   +3 more
doaj   +1 more source

Assessing Romanian financial sector stability: the importance of the international economic climate [PDF]

open access: yes
The aim of this paper is to develop an aggregate stability index for the Romanian financial system. The index which is meant to enhance the set of analysis used by the central bank to assess the financial stability accurately reflects the financial ...
Albulescu, Claudiu Tiberiu
core   +1 more source

Evaluation of the Physical Stability of Zinc Oxide Suspensions Containing Sodium Poly-(acrylate) and Sodium Dodecylsulfate. [PDF]

open access: yes, 2011
The physical stability of zinc oxide (ZnO) aqueous suspensions has been monitored during two months by different methods of investigation. The suspensions were formulated with ZnO at a fixed concentration (5 wt%), sodium poly-(acrylate), as a viscosifier,
Ahmed-Zaïd, Toudert   +5 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Study of Saturated Hydraulic Conductivity Variations in Different Aggregate Size Distributions in an Agricultural Soil

open access: yesعلوم آب و خاک, 2019
Saturated hydraulic conductivity (Ks) is one of the most important soil physical characteristics that plays a major role in the soil hydrological behaviour. It is mainly affected by the soil structure characteristics.
S. Rahmati, A. R. Vaezi, H. Bayat
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Home - About - Disclaimer - Privacy