Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Aggregate Representations of Aggregate Games [PDF]
An aggregate game is a normal-form game with the property that each player’s payoff is a function only of his own strategy and an aggregate function of the strategy profile of all players. Aggregate games possess a set of purely algebraic properties that
Stole, Lars, Martimort, David
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Monitoring Sustainable Soil Tillage Methods for Climate Change Mitigation: Aggregate Stability
Journal of Agricultural SciencesSoil aggregate stability is a critical indicator of the physical integrity, durability and quality of soil structure. It is also used as a fundamental criterion in evaluating sustainable soil management practices.
Esra Nur Gül +2 more
doaj +1 more source
Organic matter input determines structure development and aggregate formation in artificial soils
Geoderma, 2019 The formation of aggregates is considered to happen by clustering and cohesion of mineral particles and organic matter. Up to now, little is known about the role of different organic matter types within this process.
F. Bucka +4 more
semanticscholar +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
What do we know about comparing aggregate and disaggregate forecasts? [PDF]
This paper compares the performance of "aggregate" and "disaggregate" predictors in forecasting contemporaneously aggregated vector ARMA processes.
SBRANA, Giacomo, SILVESTRINI, Andrea
core
Raking Effects on Aggregate Densification and Channelling in Thickening
Advances in Materials Science and Engineering, 2019 Thickening performance is greatly influenced by aggregate densification and channelling development; however, the microstructures of aggregates and channelling are unable to directly observe because of high turbidity mud bed during thickening.
Xu Zhou +3 more
doaj +1 more source
Effect of liquid flow by pipetting during medium change on deformation of hiPSC aggregates
Regenerative Therapy, 2019 Introduction: Maintaining the pluripotency and homogeneity of human induced pluripotent stem cells (hiPSCs) requires stable culture conditions with consistent medium change.
Yuma Kato +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source