Linear Amphiphilic P(BzMA-co-DMAEMA) Statistical Copolymers: Synthesis via RAFT Polymerization and Formation of Nanoassemblies in Aqueous Media. [PDF]
Amarantos S +4 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Composite of Long Polymer Chains and Structured Silica Particles Achieves High Modulus and Low Hysteresis. [PDF]
Tan MWM +5 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Charge-Based Discrimination of Amyloids Using an Amyloid-Targeting Chemiluminescent Probe. [PDF]
Chung J, Jessup RE, Yang J.
europepmc +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Influence of Maximum Nominal Size on Macro- and Meso-Mechanical Properties of Cement-Stabilized Macadam. [PDF]
Zhou W, Deng C, Huang H.
europepmc +1 more source
Harnessing Supramolecular J-Aggregates in Deep Eutectic Solvents for Tunable NIR Photothermal and Photodynamic Therapy. [PDF]
Kumar K +7 more
europepmc +1 more source
Stress-induced alteration of small extracellular vesicles drives amyloid-beta sequestration and exacerbates Alzheimer's disease pathogenesis. [PDF]
Zehra S +13 more
europepmc +1 more source

