Results 221 to 230 of about 1,104,517 (257)

Fluorescence Detection of Alpha-Synuclein Aggregates in the Gut Using a Peptide Probe. [PDF]

ACS Chem Neurosci
Sim R, Lee J, Chieng J, Tan KH, Lim G, Foo A, Wong SH, Lim KL, Liang K.   +8 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Integrated biochar and green manure improve maize productivity and soil health under reduced nitrogen fertilization in yellow soil. [PDF]

Front Plant Sci
Wei Q, Liu P, Guo X, Zhang M, Liu L, Gu X, Zhang L, Zou Y, Li Y, Rehman M, Gou J.   +10 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Mechanical Performance of Basalt Fiber-Reinforced Fully Recycled Concrete Using Triple-Modified Recycled Aggregates. [PDF]

Materials (Basel)
Wang X, Zhou B, Cheng W, Sun Y, Xiao E, He Z.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Two-dimensional NIR-II AIE nanotheranostic probes with ultralarge Stokes shifts for surgical navigation and ablation of glioma. [PDF]

Sci Adv
Liu Y, Su X, Zhong Y, Shangguan P, Zhu J, Luo Z, Wu H, Wang D, Han T, Wang J, Shi B, Tang BZ.   +11 more
europepmc   +1 more source

Discovery of Crystallized and Weakly Coupled Aggregates of Pseudocyanine Iodide. [PDF]

J Phys Chem B
Bruncz AR, Chatterjee A, Gatica-Gutierrez H, Brasel S, Belyanin A, Gustavsson AK, Huang S.   +6 more
europepmc   +1 more source

Monetary aggregates redefined [PDF]

Anne Marie L. Gonczy
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