Results 61 to 70 of about 201,780 (239)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Visualization of supramolecular assembly by aggregation‐induced emission

Aggregate, 2023
Supramolecular architectures are constructed by the self‐assembly of small building blocks via the use of metal‐ligand coordination, π–π stacking interactions, hydrogen bonding, host‐guest interactions, and other noncovalent driving forces, which confer ...
Wu‐Jie Guo, Tuokai Peng, Wenping Zhu, Shixiang Ma, Guang Wang, Ying Li, Bin Liu, Hui‐Qing Peng   +7 more
doaj   +1 more source

Transiently Transfected Purine Biosynthetic Enzymes Form Stress Bodies [PDF]

, 2013
It has been hypothesized that components of enzymatic pathways might organize into intracellular assemblies to improve their catalytic efficiency or lead to coordinate regulation.
Cook, Lindsey, Ellington, Andrew D., Marcotte, Edward M., Swaminathan, Jagannath, Tsechansky, Mark, Zhao, Alice   +5 more
core   +4 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Ionized Nitrogen Mono-hydride Bands are Identified in the Pre-solar and Carbonado Diamond Spectra

, 2011
None of the well established Nitrogen related IR absorption bands, common in synthetic and terrestrial diamonds, have been identified in the pre-solar diamond spectra.
Adams, Amari, Anders, Andersen, Braatz, Cheung, Colangeli, Collins, Crawford, Davis, Demeny, Field, Garai, Hill, Hily-Blant, Huebner, Jones, Jones, Kagi, Koike, Lawson, Lawson, Lewis, Lewis, McNamara, Meier, Meyer, Mitchell, Mutschke, Mutschke, Persson, Samoilovitch, Schmitt, Swings   +33 more
core   +1 more source

Poly(triazolyl methacrylate) glycopolymers as potential targeted unimolecular nanocarriers [PDF]

, 2019
© The Royal Society of Chemistry 2019.Synthetic glycopolymers are increasingly investigated as multivalent ligands for a range of biological and biomedical applications.
Fernandez-Trillo, F., Foralosso, R., He, Y., King, P.J.S., Laughton, C. A., Madeira do O, J., Mantovani, G., Mastrotto, F., Stolnik, S., Styliari, Ioanna Danai, van der Walle, C.F., Xerri, R.M., Yilmaz, G.   +12 more
core   +4 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

An unexpected dual-emissive luminogen with tunable aggregation-induced emission and enhanced chiroptical property

Nature Communications, 2022
Organic materials with both aggregation induced emission (AIE) and aggregation-caused quenching (ACQ) effects that can emit with multiple wavelengths in the solution and aggregated state are rarely reported.
Xinyu Zhang, Huiqing Liu, Guilin Zhuang, Shangfeng Yang, Pingwu Du   +4 more
doaj   +1 more source

Importance of Soil Quality in Environment Protection [PDF]

, 2007
Soil quality can be characterised by the harmony between it’s physical and biological state and the fertility. From the practical crop production viewpoint, some important contrasting factors of soil quality are: (1) soil looseness – compaction; (2 ...
Birkás, Márta, Bottlik, László, Kalmár, Tibor, Takács, Tamás   +3 more
core   +1 more source

Mass Spectrometric Characterization of Oligomers in Pseudomonas aeruginosa Azurin Solutions [PDF]

, 2011
We have employed laser-induced liquid bead ion desorption mass spectroscopy (LILBID MS) to study the solution behavior of Pseudomonas aeruginosa azurin as well as two mutants and corresponding Re-labeled derivatives containing a Re(CO)_(3)(4,7-dimethyl-1,
Brutschy, Bernd, Gray, Harry B., Hof, Martin, Soklová, Lucie, Sýkora, Jan, Vlček, Antonín, Jr., Williamson, Heather   +6 more
core   +2 more sources