Results 141 to 150 of about 2,239,330 (392)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Does consistent aggregation really matter? [PDF]
Consistent aggregation ensures that behavioural properties which apply to disaggregate relationships apply also to aggregate relationships. The agricultural economics literature which has tested for consistent aggregation or measured statistical bias and/
Davis, George C., Shumway, C. Richard
core +4 more sources
Wearable Sensors Based on Stretchable Organic Transistors
Organic electrochemical transistors (OECTs) hold potential for in‐sensor computing and wearable healthcare systems. Nevertheless, their inherent limitations in stretchability and conformability hinder their scalability and practical deployment.
Yang Liu, Deyang Ji
doaj +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
AGGREGATION OF DYES BOUND TO POLYANIONS [PDF]
Dan F. Bradley, Merrill K. Wolf
openalex +1 more source
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Enzymatically catalyzed molecular aggregation
The dynamic modulation of the aggregation process of small molecules represents an important research objective for scientists. However, the complex and dynamic nature of internal environments in vivo impedes controllable aggregation processes of single ...
Wen-Jin Wang+13 more
doaj +1 more source
Internal stresses in low-Reynolds-number fractal aggregates [PDF]
We present a numerical model of fractal-structured aggregates in low-Reynolds-number flows. Assuming that aggregates are made of cubic particles, we first use a boundary integral method to compute the stresses acting on the boundary of the aggregates. From these external stresses, we compute the stresses within the aggregates in order to gain insights ...
arxiv
An Unfolding-Based Semantics for Logic Programming with Aggregates [PDF]
The paper presents two equivalent definitions of answer sets for logic programs with aggregates. These definitions build on the notion of unfolding of aggregates, and they are aimed at creating methodologies to translate logic programs with aggregates to normal logic programs or positive programs, whose answer set semantics can be used to defined the ...
arxiv