Results 161 to 170 of about 2,239,330 (392)

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

The commercial antibiotics with inherent AIE feature: In situ visualization of antibiotic metabolism and specifically differentiation of bacterial species and broad-spectrum therapy

open access: yesBioactive Materials, 2023
The research on pharmacology usually focuses on the structure-activity relationships of drugs, such as antibiotics, to enhance their activity, but often ignores their optical properties.
Bingnan Wang   +8 more
doaj  

Arrow's Theorem in Judgement Aggregation [PDF]

open access: yes
In response to recent work on the aggregation of individual judgements on logically connected propositions into collective judgements, it is often asked whether judgement aggregation is a special case of Arrowian preference aggregation.
Christian List, Franz Dietrich
core  

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Unraveling the crucial role of trace oxygen in organic semiconductors

open access: yesNature Communications
Optoelectronic properties of semiconductors are significantly modified by impurities at trace level. Oxygen, a prevalent impurity in organic semiconductors (OSCs), has long been considered charge-carrier traps, leading to mobility degradation and ...
Yinan Huang   +17 more
doaj   +1 more source

Recent Progress in 2-Dimensional Organic–Inorganic Heterojunction Optoelectronic Devices

open access: yesAdvanced Devices & Instrumentation
Two-dimensional (2D) materials have attracted significant attention in the fields of electronics and optoelectronics because of their defect-free surfaces, ultrahigh carrier mobility, and exceptional mechanical, optical, and electrical properties ...
Huchao Li   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy