Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Effects of plasma donation on blood rheology and peripheral vascular function. [PDF]
Steele AR +3 more
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Potential Mechanisms of Platelet Dysfunction and Bleeding in Acid Sphingomyelinase Deficiency. [PDF]
Sysoev M +3 more
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Alzheimer's Disease in the Era of Geroscience: Mechanisms, Biomarkers, and Therapeutic Prospects. [PDF]
Chmielewski PP.
europepmc +1 more source
Comparison of variably specific Bruton tyrosine kinase inhibitors on platelet aggregation mediated by Fcγ receptor (FcγR) IIa, glycoprotein VI, and platelet endothelial aggregation receptor (PEAR) 1: implications for Bruton tyrosine kinase inhibitors as antithrombotic therapy. [PDF]
Kartika T +4 more
europepmc +1 more source
Cognitive dysfunction in MASLD is linked to platelet activation. [PDF]
Chen J, Cheng C, Wang H, Yu T.
europepmc +1 more source
Trust-Aware Environmental State Consensus for Smart Agriculture with TEE-Enabled Sensing and Byzantine-Resilient Blockchain Coordination. [PDF]
Li L +7 more
europepmc +1 more source
CCP-YOLO: An Improved YOLOv11n Algorithm for Steel Surface Defect Detection. [PDF]
Xiao L, Li P, Wang C, Zheng H, Xu Y.
europepmc +1 more source

