Results 41 to 50 of about 462,579 (217)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
TMEM106B aggregation in neurodegenerative diseases: linking genetics to function
Molecular Neurodegeneration, 2023 Background Mutations of the gene TMEM106B are risk factors for diverse neurodegenerative diseases. Previous understanding of the underlying mechanism focused on the impairment of lysosome biogenesis caused by TMEM106B loss-of-function. However, mutations
Hai-Shan Jiao, Peng Yuan, Jin-Tai Yu
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Analysis and Selection of Appropriate Aggregation Function for Calculating of Leachate Pollution Index of Landfill Lysimeter [PDF]
Iranica Journal of Energy and Environment, 2012 A technique to quantify the leachate pollution potential of solid waste landfills on a comparative scale using an index known as the leachate pollution index (LPI) developed.
Islam M. Rafizul +2 more
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The in vitro effect of antirheumatic drugs on platelet function
Platelets, 2020 Several antirheumatic drugs lower the cardiovascular risk among rheumatoid arthritis patients. It is, however, unknown whether inhibition of platelet function contributes to this risk reduction.
Camilla Brødsgaard Nielsen +4 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Prognostic Value of Platelet Aggregation Function in Patients with laryngeal Carcinoma
International Journal of General Medicine, 2023 Minghua Li,1,* Jiawei Gui,1,* Hao Wang,2 Jun An,3 Ruoqing Wu,1 Xiaotong Liu,1 Bo Wu,1 Hui Xiao1 1Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, People’s Republic of
Li M +7 more
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On aggregation of metric structures: the extended quasi-metric case [PDF]
International Journal of Computational Intelligence Systems, 2013 In 1981, J. Borsík and J. Doboš studied and solved the problem of how to merge, by means of a function, a (not necessarily finite) collection of metrics in order to obtain a single one as output. Later on, in 2010, G. Mayor and O.
Sebastià Massanet, Oscar Valero
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
New Results About Aggregation Functions of Quasi-Pseudometric Modulars
MathematicsIn recent studies, Bibiloni-Femenias, Miñana, and Valero characterized the functions that aggregate a family of (quasi-)(pseudo)metric modulars defined over a fixed set X into a single one.
Alejandro Fructuoso-Bonet +1 more
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