Results 51 to 60 of about 1,169,320 (303)

Small heat-shock proteins: important players in regulating cellular proteostasis [PDF]

, 2015
Small heat-shock proteins (sHsps) are a diverse family of intra-cellular molecular chaperone proteins that play a critical role in mitigating and preventing protein aggregation under stress conditions such as elevated temperature, oxidation and infection.
Carver, John A., Ecroyd, Heath, Meehan, Sarah, Treweek, Teresa M.   +3 more
core   +1 more source

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster   +13 more
wiley   +1 more source

Paraspeckles: Paragons of functional aggregation [PDF]

Journal of Cell Biology, 2015
Low-complexity proteins undergo phase separation in vitro, forming hydrogels or liquid droplets. Whether these form in vivo, and under what conditions, is still unclear. In this issue, Hennig et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201504117) show that formation of the paraspeckle, a nuclear body that regulates gene expression ...
Courchaine, Edward, Neugebauer, Karla M.
openaire   +2 more sources

Patient Activation in Childhood, Adolescent, and Young Adult Cancer Survivors: Current Insights and Implications for Survivorship Care—A Systematic Review From the e‐QuoL Project

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Patient activation—encompassing knowledge, confidence, and skills in managing individual's health—is a cornerstone of person‐centered care. However, its significance among childhood, adolescent, and young adult cancer survivors (CAYACS) remains unexplored. This article examines the application of the 13‐item Patient Activation Measure (
Charlotte Demoor‐Goldschmidt, Anne Maas, Gisela Michel, Amandine Bertrand, Kristen E. T. Thornton, Martine Bellanger, Anna‐Liesa Filbert, Desiree Grabow, Monica Muraca, Katharina Roser, Sara Oberti, Jelena Roganovic, Hanne Cathrine Lie   +12 more
wiley   +1 more source

Utility of Computed Tomography Surveillance of Asymptomatic Infection in Children and Young Adults Before Allogeneic Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Asymptomatic infection poses a significant risk for children undergoing hematopoietic stem cell transplantation (HSCT). Pre‐transplant surveillance computed tomography (CT) is commonly used to identify occult infection, though its diagnostic yield remains uncertain.
Tyler Obermark, Pradipta Debnath, Rama S. Ayyala, Lara A. Danziger‐Isakov, Jane Koo, Kasiani C. Myers, William R. Otto, Aki Tanimoto, Andrew T. Trout, Cara E. Morin   +9 more
wiley   +1 more source

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia, Giulia Reggiani, Elizabeth J. Maran, Maria Elisa Delle Fave, Ilaria Baido, Anna Chiara Frigo, Maria Paola Boaro, Raffaella Colombatti   +7 more
wiley   +1 more source

Choquet-Inspired Aggregation Functions

Information Fusion
In this work, we propose a new family of aggregation functions inspired by the well-known Choquet integral. To build these functions, we replace the measure in the definition of the Choquet integral by an appropriate function. We study the properties of these aggregation functions and explore the relations with some other common aggregation functions ...
H. Bustince, R. Mesiar, G.P. Dimuro, J. Fernandez, J. Lafuente, B. De Baets   +5 more
openaire   +2 more sources

Weibull-type limiting distribution for replicative systems

, 2011
The Weibull function is widely used to describe skew distributions observed in nature. However, the origin of this ubiquity is not always obvious to explain.
Jean-Yves Fortin, Junghyo Jo, M. Y. Choi, O. Kallenberg, T. E. Harris, W. Weibull   +5 more
core   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Orness For Idempotent Aggregation Functions [PDF]

Axioms, 2017
Aggregation functions are mathematical operators that merge given data in order to obtain a global value that preserves the information given by the data as much as possible. In most practical applications, this value is expected to be between the infimum and the supremum of the given data, which is guaranteed only when the aggregation functions are ...
Legarreta, Leire, Lizasoain Iriso, María Inmaculada, Mardones Pérez, Iraide   +2 more
openaire   +5 more sources