Results 111 to 120 of about 1,608,848 (335)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Fast micro and slow macro: can aggregation explain the persistence of inflation? [PDF]

open access: yes
An aggregation exercise is proposed that aims at in-vestigating whether the fast average adjustment of the disaggregate inflation series of the euro area CPI translates into the slow adjustment of euro area aggregate inflation.
Altissimo, Filippo   +2 more
core  

The scheduling of sparse matrix-vector multiplication on a massively parallel dap computer [PDF]

open access: yes, 1991
An efficient data structure is presented which supports general unstructured sparse matrix-vector multiplications on a Distributed Array of Processors (DAP). This approach seeks to reduce the inter-processor data movements and organises the operations in
Andersen, J, Mitra, G, Parkinson, D
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

EVALUATION OF TERRITORIAL COMPETITIVENESS. CASE STUDY: SOUTH – EAST REGION AND TULCEA COUNTY [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2016
The concept of competitiveness still represents an important debate subject for the academic and economic environment. Differences of opinion regarding its nature, of macro or micro economic, continue to motivate the identification of common elements ...
Mihai Alexandru CHIȚEA, Ion DONA
doaj  

Pathogenesis Interrelation of Insufficiency of Erythrocytes Antiradical Protection and Disturbance of Blood Rheological Properties in Bacterial Endotoxicosis

open access: yesПроблемы особо опасных инфекций, 2009
Among the leading pathogenesis factors of disorders of regional blood flow and microcirculation in plague intoxication induced by Y. pestis lipopolysaccharide (LPS) are decreases of blood viscosity at various shift rates, indices of erythrocyte ...
G.A. Afanas`eva   +2 more
doaj   +1 more source

Unbiased Estimation of the Half-Life to Price Index Convergence among US Cities [PDF]

open access: yes
Cecchetti et al. (2002) estimate the half-life to price index convergence among U.S. cities to be approximately nine years. Although they correct for the small-sample bias in their panel estimate of the half-life, they do not adjust for biases that may ...
Hiranya K. Nath, Jayanta Sarkar
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Structure and performance study of ad hoc microsat constellation with secondary launches

open access: yesAdvances in Mechanical Engineering, 2016
In this article, an ad hoc microsat constellation based on secondary launches is proposed to meet the demands for the constellation characteristics. Research on its structural design and characteristics is carried out. First, constellation characteristic
Guan Xin, Hua Bing, Wu Yunhua
doaj   +1 more source

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