Results 91 to 100 of about 1,608,848 (335)
International Journal of Molecular SciencesPreeclampsia (PE) is a hypertensive disease characterized by proteinuria, endothelial dysfunction, and placental hypoxia. Reduced placental blood flow causes changes in red blood cell (RBC) rheological characteristics.
Anika Alexandrova-Watanabe +7 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Disposable Blood-on-a-Chip for Simultaneous Measurement of Multiple Biophysical Properties
Micromachines, 2018 Biophysical properties are widely used to detect pathophysiological processes of vascular diseases or clinical states. For early detection of cardiovascular diseases, it is necessary to simultaneously measure multiple biophysical properties in a ...
Yang Jun Kang
doaj +1 more source
The weekly structure of US stock prices [PDF]
, 2010 In this paper we use fractional integration techniques to examine the degree of integration of four US stock market indices, namely the Standard and Poor, Dow Jones, Nasdaq and NYSE, at a daily frequency from January 2005 till December 2009.
Caporale, GM, Gil-Alana, LA
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Understanding Price Variation Across Stores and Supermarket Chains: Some Implications for CPI Aggregation Methods [PDF]
The empirical literature on price indices consistently finds that aggregation methods have a considerable impact, particularly when scanner data are used.
Kevin J. Fox, Lorraine Ivancic
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Consistent Simple Sum Aggregation over Assets [PDF]
This paper discusses the issue of consistent simple sum aggregation over assets within the context of expected utility maximizing investors. The first part of the paper extends the Hicks and Leontief aggregation theorems of consumer choice theory to the ...
David S. Jones
core
Characterizing Flight Aggregation of the Southern Pine Beetle [PDF]
, 1979 Spatial aggregation patterns of flying southern pine beetles, Dendroctonus frontalis Zimm., were studied using a systematic grid of sticky flight traps placed in 3 beetle infestations.
Coster, Jack E., Johnson, Paul C.
core +1 more source