Results 111 to 120 of about 24,615 (309)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Choquet integral for the aggregation of interval scales in multicriteria decision making [PDF]

open access: yes
This paper addresses the question of which models fit with information concerning the preferences of the decision maker over each attribute, and his preferences about aggregation of criteria (interacting criteria).
Michel Grabisch, Christophe Labreuche
core  

THE IMPORTANCE OF AGGREGATION OPERATOR CHARACTERISTICS IN MARKETING RESEARCH [PDF]

open access: yes, 2008
: Our paper demonstrates that aggregation operator characteristics count as a promising avenue for applied fuzzy set research. It is shown by means of two cases that these characteristics are particularly valuable as proxies for hard to measure domain ...
Benoît Depaire   +4 more
core  

Some Issues on Properties of the Extended IOWA Operators in Cubic Group Decision Making

open access: yesJournal of New Theory, 2018
The concept of this paper to study some IOWA operator to aggregating the individual cubic preference relations (CPR). This paper deal further the study of their properties of group decision problems with the help of CPR, we have proved that the ...
Muhammad Shakeel   +2 more
doaj  

Entrepreneurship and Decision-Making in Latin America

open access: yesInnovar: Revista de Ciencias Administrativas y Sociales, 2014
The principal purpose of this paper is to analyze different methods for decision making, with a focus on entrepreneurship in Latin America. Decision-making methods may be informed by aggregation operators that are based on the use of probabilities ...
José M. Merigó, Marta Peris-Ortiz
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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