Results 141 to 150 of about 1,636,355 (323)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
How to score alternatives when criteria are scored on an ordinal scale [PDF]
We address in this paper the problem of scoring alternatives when they are evaluated with respect to several criteria on a finite ordinal scale $E$.
Michel Grabisch
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Modular relaxed indistinguishability and the aggregation problem
AIMS MathematicsThe notion of indistinguishability operator plays a central role in a large number of problems that arise naturally in decision-making, artificial intelligence, and computer science. Among the different issues studied for these operators, the aggregation
M. D. M. Bibiloni-Femenias, O. Valero
doaj +1 more source
Journal of Applied Mathematics, 2012 Two induced aggregation operators with novelly designed TOPSIS order-inducing variables are proposed: Induced Interval-valued Intuitionistic Fuzzy Hybrid Averaging (I-IIFHA) operator and Induced Interval-valued Intuitionistic Fuzzy Hybrid Geometric (I ...
Jun-Ling Zhang, Xiao-Wen Qi
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The induced 2-tuple linguistic generalized OWA operator and its application in linguistic decision making [PDF]
We present the induced 2-tuple linguistic generalized ordered weighted averaging (2-TILGOWA) operator. This new aggregation operator extends previous approaches by using generalized means, order-inducing variables in the reordering of the arguments and ...
Anna M. Gil-Lafuente +1 more
core +1 more source
A discussion on aggregation operators. [PDF]
, 2004 It has been lately made very clear that aggregation processes can not be based upon a unique binary operator. Global aggregation operators have been therefore introduced as families of aggregation operators {Tn}n , being each one of these Tn the n-ary operator actually amalgamating information whenever the number of items to be aggregated is n.
Gómez, Daniel, Montero, Javier
openaire +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source