Results 141 to 150 of about 401,541 (313)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Making Sense of the Aggregator Bank [PDF]
On Tuesday, 10 February 2009, Treasury Secretary Geithner proposed the aggregator bank ("public-private investment fund") as a key instrument to resolve the financial crisis.
Cramton Peter, Ausubel Lawrence M
core +1 more source
dnet-basic-aggregator: release 1.1.1
, 2016 <a class="anchor" href="#d-net-software-toolikt"><span class="octicon octicon-link"></span></a>D-Net Software Toolikt <p>This is a minimal instance of the D-Net software toolkit, a software framework for the realization of ...
Andrea Mannocci +2 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
EnergiesThe rapid expansion of energy storage integration has not provided sufficient time to strengthen and expand the transmission and distribution network. This issue can lead to PCC congestion in green multi-microgrid (MMG) systems.
Farshad Khavari, Jay Liu
doaj +1 more source
, 2011 My PhD thesis aims at carrying out a complete analysis of problems of combinatorial aggregation, with particular attention to the binary case, in which a set of individuals each make a choice over a finite number of issues, and such choices have to be aggregated into a collective one.
openaire +4 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2013 Presentation for the 2013 International Internet Preservation Consortium General Assembly. Discusses the current release and development status of the Memento Aggregator, along with future goals and ...
Rosenthal, David S. H. +2 more
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Aggregates and categories of aggregates
ITlib.Informačné technológie a knižnice, 2023 Margit Németh-Takács, Mária Borbély
openaire +1 more source