Results 101 to 110 of about 270,728 (294)

Stability in aggression revisited

open access: yes, 2012
Research on the stability of aggression tends to show patterns of continuity and to a lesser extent discontinuity. In this study, we provide a review of research published in four specific journals that target the stability of aggression across distinct ...
P. Farrington, David   +7 more
core   +1 more source

Investigating proactive aggression in patients with borderline personality disorder and major depressive disorder using a modified version of the Taylor aggression paradigm

open access: yesFrontiers in Psychology
IntroductionInappropriate reactive (provoked) aggression is common in various psychiatric disorders, including Borderline Personality Disorder (BPD) and, to a lesser extent, Major Depressive Disorder (MDD).
Sara Boccadoro   +7 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Neuro-cognitive models of aggression, the antisocial personality disorders and psychopathy [PDF]

open access: yes, 2001
This paper considers neurocognitive models of aggression and relates them to explanations of the antisocial personality disorders. Two forms of aggression are distinguished: reactive aggression elicited in response to frustration/threat and goal directed,
Blair, R.J.R.
core  

Hegemonic masculinity and aggression in South Africa [PDF]

open access: yes, 2002
This thesis explores 'Hegemonic Masculinity and Aggression in South Africa'. It incorporates three separate, but sequential research parts, each building on the findings of the previous part in order to realise general research ...
Luyt, Russell
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

The Influence of Socioeconomic Status on Adolescent Aggressive Behavior: The Mediating Roles of Normative Beliefs About Aggression and Aggressive Affect

open access: yesBehavioral Sciences
Adolescence is a period in which the frequency of aggressive behavior increases. However, the relationship between socioeconomic status (SES) and different types of aggression remains unclear.
Yuhan Yang   +3 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Aggression among Preschool Children within the Framework of Temperament, Attachment and Parental Attitudes

open access: yesPsikiyatride Güncel Yaklaşımlar
Aggression is a common problem in preschool children. The relationship between aggressive behaviors in early ages and psychopathologies in later years has been shown in previous studies.
Rabia Nur Kodak, Halime Şenay Güzel
doaj   +1 more source

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