Results 111 to 120 of about 817,186 (380)
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Building a Bond: Longitudinal Relations between Interpersonal School Climate, Student Awareness and Reporting of Violence, and Peer Victimization and Aggression in Adolescents [PDF]
, 2017 High prevalence rates and negative outcomes of peer-based aggression and victimization during early adolescence underscore the need to identify causes and consequences of these outcomes.
Behrhorst, Kathryn
core +1 more source
TERAPI BERMAIN KELOMPOK UNTUK MENINGKATKAN REGULASI EMOSI PADA ANAK DENGAN PERILAKU AGRESI [PDF]
, 2023 Childhood is the most vulnerable period of physical and mental development. The emotional development that occurs during this period will play a very important role in the future of children.
Millah, Wahidah Nurul
core
The pleasure of revenge: retaliatory aggression arises from a neural imbalance toward reward.
Social Cognitive and Affective Neuroscience, 2016 Most of daily life hums along peacefully but provocations tip the balance toward aggression. Negative feelings are often invoked to explain why people lash out after an insult.
D. Chester, C. DeWall
semanticscholar +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Persistence of aggression into adulthood in detained adolescent females
Comprehensive Psychiatry, 2014 Objective: Although detained adolescent females show high rates of severe aggression, we know little about the long-term impact of this risk-behavior. Furthermore, qualitative differences in aggression between males and females argue for gender specific ...
Anne A. Krabbendam +5 more
doaj
Journal of Abnormal Child Psychology, 2016 This study was designed to examine whether proactive and reactive aggression are meaningful distinctions at the variable- and person-based level, and to determine their associated behavioral profiles. Data from 587 adolescents (mean age 15.6; 71.6 % male)
K. Smeets +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
The neurobiological basis of human aggression: A review on genetic and epigenetic mechanisms
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2016 Aggression is an evolutionary conserved behavior present in most species including humans. Inadequate aggression can lead to long‐term detrimental personal and societal effects.
Regina Waltes +2 more
semanticscholar +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source