Results 111 to 120 of about 752,343 (341)

Childhood aggression

Neuroscience and Biobehavioral Reviews, 2018
This study provides a synthesis of meta-analyses and systematic reviews on non-pharmacological treatments for childhood aggression. Treatments referred to universal prevention, selective prevention, indicated prevention, or intervention (Mrazek and Haggerty, 1994). Seventy-two meta-analyses and systematic reviews met the inclusion criteria. We describe
Hendriks, A M, Bartels, Meike, Colins, O F, Finkenauer, C   +3 more
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Investigating proactive aggression in patients with borderline personality disorder and major depressive disorder using a modified version of the Taylor aggression paradigm

Frontiers in Psychology
IntroductionInappropriate reactive (provoked) aggression is common in various psychiatric disorders, including Borderline Personality Disorder (BPD) and, to a lesser extent, Major Depressive Disorder (MDD).
Sara Boccadoro, Philippa Hüpen, Philippa Hüpen, Adrian Raine, Ute Habel, Ute Habel, Lisa Wagels, Lisa Wagels   +7 more
doaj   +1 more source

THE PRACTICE OF NATIONAL POLITICAL EXPERTISE IN THE CONTEXT OF GLOBAL CHALLENGES CAUSED BY THE COVID-19 PANDEMIC AND THE FULL-SCALE AGGRESSION OF THE RUSSIAN FEDERATION: FEATURES AND RISKS

, 2023
Yu.-A.I. Nykorovych
openalex   +1 more source

Caregiver Behaviors Associated With Emotion Regulation in High-Risk Preschoolers [PDF]

, 2018
Children who witness violence are at risk for developing a range of developmental problems, including deficits in understanding and regulating. The ability to adaptively manage emotions is associated with children’s mental health and their social and ...
Caiozzo, Christina, Grych, John H., Yule, Kristen   +2 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

“Here I Come to Save the Day!” Does Parental Mediation Moderate Associations between Superhero Exposure and Behavior in Young Boys? [PDF]

, 2013
Studies have shown that superheroes are very popular among preschool boys, but research on the effect of exposure to superhero media and toys is limited.
Coyne, Sarah, Frueh, Helena, Garcia, Cynthia, Linder, Jennifer   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The crime of aggression in international law problems of the development of a universal definition [PDF]

, 2018
Oksana VOLOSCHUK
openalex   +1 more source