Results 131 to 140 of about 752,343 (341)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Protection costs, transaction costs,and economic theory [PDF]

open access: yes
Contractual reductionism takes market exchange as the ubiquitous form of economic organization throughout history. Transactions costs are accordingly regarded as the costs of running any economic system in general.
Vahabi, Mehrdad
core   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

On the Margins of Friendship: Aggression in an Elementary School Peer Group

open access: yes, 2019
This article uses qualitative data from a larger study of two elementary schools in a rural city of about 15,000 people in the Midwestern United States.
Harger, Brent D.
core  

Fractal analysis of CE CT lung tumours images [PDF]

open access: yes, 2007
AIM The fractal dimension (FD) of a structure provides a measure of its complexity. This pilot study aims to determine FD values for lung cancers visualised on Computed Tomography (CT) and to assess the potential for tumour FD measurements to provide an ...
Al-Kadi, Omar S, Watson, Des
core  

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Personality and behavioral factors related to drink-driving among young males : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

open access: yes, 1999
The study aimed to replicate the findings of research which highlighted a number of personality and behavioural variables that effect an individuals drink-driving frequency, and intoxication level while driving.
McKillop, David
core  

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Children’s Perceptions of Intimate Partner Violence: Causes, Consequences, and Coping [PDF]

open access: yes, 2011
Children’s appraisals of conflictual and aggressive parental interactions mediate their effect on children’s adjustment. Previous studies have relied almost exclusively on selfreport questionnaires to assess appraisals; consequently we know little about ...
DeBoard-Lucas, Renee L., Grych, John H.
core   +1 more source

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