Results 131 to 140 of about 817,186 (380)
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Ostracism Increases Automatic Aggression: The Role of Anger and Forgiveness
Frontiers in Psychology, 2019 While research on the “ostracism-aggression” link has focused on controlled processes in aggression, little effort has been devoted to examining the relation between ostracism and automatic aggression.
Denghao Zhang +5 more
doaj +1 more source
Aggression and Self‐Regulation of Population Size in Deermice [PDF]
, 1967 M. C. Healey
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
PREVENTING AGGRESSION IN YOUTH: A SOCIAL ASPECT
Неперервна професійна освіта: теорія та практика, 2020 The article deals with the phenomenon of aggression as a social phenomenon that has both social and biological (psychological) conditions. Based on the analysis of scientific sources the author has classified the types of aggression, emphasizing that the
Maria Сhmielewska
doaj +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Ericka L. Daniels - Distinguishing between Risk Factors for Aggression Perpetration, and Victimization in Adolescent Dating Relationships [PDF]
, 2013 Objective: Aggression in adolescent romantic relationships occurs at a substantial rate and has negative effects on victims. This study will investigate risk factors that may anticipate a person’s role as a victim or perpetrator of aggression in dating ...
Daniels, Ericka L.
core +1 more source
Intensity of attack, displacement and verbal aggression [PDF]
, 1968 Donald L. Mosher, Luis M. Proenza
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source