Results 91 to 100 of about 384,572 (335)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Penyesuaian Keluarga, Pengasuhan, Kekerasan dalam Pengasuhan, dan Agresivitas pada Anak Usia Sekolah
Jurnal Ilmu Keluarga dan Konsumen, 2018 Inappropriate parenting can trigger emotional problems that lead to negative behavior, one of that is aggressiveness. This study aimed to analyze the effect of family adjustment, parenting, and violence in parenting on aggressiveness in among elementary
Ismayanti Pratiwi +2 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Proceedings of the National Academy of Sciences, 2018 Have aggression and violence been ramped up in human evolution or dialed down? This sounds like a question that empirical research might have settled long ago, but it remains strangely contentious. In PNAS, Richard Wrangham (1) proposes that debates persist because too many evolutionary anthropologists mistakenly conceive of aggression as unitary and ...
openaire +2 more sources
Eccrine Porocarcinoma, A Rare Aggressive Malignant Adnexal Tumor of the Skin: A Case Report [PDF]
, 2021 Nishith Vaddeboina
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Indian Dermatology Online Journal, 2014 Myxoid tumors are a heterogeneous group of lesions characterized by a marked abundance of extra cellular mucoid (myxoid) matrix.[1] The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with recurrence.[2] A case of aggressive angiomyxoma arising from the vagina in a 55-year-old woman is reported for its
L Padmavathy +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Order Submission Strategies and Information: Empirical Evidence from the NYSE [PDF]
We investigate the role of asymmetric information in affecting order submission strategies. Order aggressiveness depends on the state of the order book and on the asset dynamics. We find that the most important determinants are the depth on the same side
Alessandro Beber, Cecilia Caglio
core