Results 61 to 70 of about 136,175 (267)
Penyesuaian Keluarga, Pengasuhan, Kekerasan dalam Pengasuhan, dan Agresivitas pada Anak Usia Sekolah
Inappropriate parenting can trigger emotional problems that lead to negative behavior, one of that is aggressiveness. This study aimed to analyze the effect of family adjustment, parenting, and violence in parenting on aggressiveness in among elementary
Ismayanti Pratiwi +2 more
doaj +1 more source
The Level of Aggressiveness During Karate Practice of Inmates in Correctional Settings
Karate is known to enhance cognitive functioning, emotional well-being, and self-regulation and to contribute to an overall behavior rehabilitation process. However, few data are available on the impact of practicing karate in adult prison inmates.
Jérôme Frigout +3 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Alcoholism is today the greatest medical and social problem. Due to the fact that it is frequently connected with aggressiveness, it can also be defined as a great and frequent forensic problem. The authors investigate the issue to what extent aggressiveness is medically justified.
Dodig, Goran +4 more
openaire +6 more sources
Aggressive Man and Aggressive Beast
Aggression-on campuses, in city streets, in Vietnam, in the Middle East-makes headlines every day. But just what is aggression? Strictly speaking, aggression refers to actual or symbolic attack upon another individual. In the interest of reading ease, however, we use the terms aggression and aggressive behavior more or less interchangeably in this ...
Allen W. Stokes, Lois M. Cox
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Aggressive angiomyxoma is a rare mesenchymal tumor that most commonly arises in the vulvovaginal region, perineum, and pelvis of women. The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with local recurrence. Patients often present with nonspecific symptoms which are frequently misdiagnosed with more
Brian J, Sutton, Jennifer, Laudadio
openaire +2 more sources
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source

