From Neuron‐Centric to Glia‐Centric: How Aging Glial Networks Drive Neurodegenerative Disease
Journal of Neurochemistry, Volume 170, Issue 1, January 2026.During aging, progressive alterations in glial networks reshape intercellular communication within the central nervous system. In the young brain, astrocytes and microglia actively regulate metabolic, immune, and synaptic processes that sustain neural circuit stability.
Lívia de Sá Hayashide +5 more
wiley +1 more source
The brattleboro rat displays a natural deficit in social discrimination that is restored by clozapine and a neurotensin analog. [PDF]
, 2009 Cognitive deficits in schizophrenia are a major source of dysfunction for which more effective treatments are needed. The vasopressin-deficient Brattleboro (BRAT) rat has been shown to have several natural schizophrenia-like deficits, including ...
Feifel, D +5 more
core +2 more sources
Interoperabilità e accessibilità dell'informazione geografica, i lavori in corso di AgID
, 2020 Nell’ambito della strategia nazionale per una infrastruttura per l’informazione del settore pubblico come base di conoscenza di tutte le risorse informative delle pubbliche amministrazioni, AgID (Agenzia per l’Italia Digitale) ha messo in campo linee di azione specifiche.
Ciasullo, Gabriele, Rotundo, Antonio
openaire +1 more source
Cognitive dysfunction and dementia in Parkinson's disease [PDF]
, 2004 Parkinson's disease (PD) is a slowly progressive neurodegenerative disorder mainly characterized by degeneration of dopaminergic neurons in the substantia nigra and the ventral tegmental area, in combination with a varying loss of central noradrenergic ...
Bosboom, JL +2 more
core +1 more source
Agar gel immunodiffusion test (AGID) evaluation for detection of bovine paratuberculosis in Rio de Janeiro, Brazil [PDF]
Letters in Applied Microbiology, 2002 The aim of this study is to evaluate the AGID serological test for detection of antibodies anti-Mycobacterium paratuberculosis and its possible adoption as diagnostic method in our field conditions.Bovine serum samples from dairy herds in Rio de Janeiro State, Brazil, were screened for the presence of antibodies against Myco.
R, Ferreira, L S, Fonseca, W, Lilenbaum
openaire +2 more sources
Valutazione di alcune performance diagnostiche di kit ELISA per la diagnosi sierologica di Anemia Infettiva Equina (AIE) [PDF]
, 2012 Data on evaluation of some diagnostic parameters of all ELISA kits available in Italy for the serodiagnosis of AIE are presented and discussed. Ten laboratories were involved using a panel of 30 sera ran with 4 commercial kits and 2 in-house kits.
Angioini, A. +11 more
core
L'importante ruolo degli open data nelle emergenze
GEOmedia, 2016 The important role of open data in emergencies During emergencies, the geographic information plays a very important and delicate role becoming the main tool to understand what happened and to take decisions.
Maurizio Napolitano
doaj +2 more sources
, 2017 Proving that a cryptographic protocol is correct for secrecy is a hard task. One of the strongest strategies to reach this goal is to show that it is increasing, which means that the security level of every single atomic message exchanged in the protocol,
Fattahi, Jaouhar +4 more
core +1 more source
Striatal vs extrastriatal dopamine D2 receptors in antipsychotic response - a double-blind PET study in schizophrenia [PDF]
, 2007 Blockade of dopamine D2 receptors remains a common feature of all antipsychotics. It has been hypothesized that the extrastriatal (cortical, thalamic) dopamine D2 receptors may be more critical to antipsychotic response than the striatal dopamine D2 ...
AA Lammertsma +48 more
core +1 more source
The Role of Identity Crises in Addiction and Recovery
Journal of Applied Philosophy, Volume 42, Issue 3, Page 1059-1075, July 2025.ABSTRACT In this article, we argue that felt discontinuity of self plays a role in recovery from substance use disorders. We rely on a view of the self that identifies continuity of the self with the maintenance of a self‐concept, and we use it to propose an explanation of how individuals with substance use disorders form concepts of self around those ...
Nada Gligorov, Ethan Cowan
wiley +1 more source