The Age of the Crusades. James M. LudlowThe Latin Kingdom of Jerusalem. 1099 to 1291 A. D.C. R. ConderL'Islam, Impressions et Études. Henry de CastriesDer Geisteskampf des Christentums gegen den Islam, bis zur Zeit der Kreuzzüge. Adolf Keller [PDF]
Oliver J. Thatcher
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Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Improving Lives through Evidence-Based Health Promotion Programs: A National Priority
Richard eBirkel+9 more
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Introduction and reconciliation of the ROS and aging paradoxes [PDF]
This paper suggests that aging is influenced synthetically by pro-aging factors such as ROS and anti-aging factors such as protective responses. The anti-aging effect may be side effects of retrograde responses motivated against adverse circumstances. ROS may be more closely correlated with metabolism rather than aging.
arxiv
Jewish Life in the Middle Ages. Israel Abrahams [PDF]
Joseph K. Arnold
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Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
Molecule-dynamic-based Aging Clock and Aging Roadmap Forecast with Sundial [PDF]
Addressing the unavoidable bias inherent in supervised aging clocks, we introduce Sundial, a novel framework that models molecular dynamics through a diffusion field, capturing both the population-level aging process and the individual-level relative aging order.
arxiv
The Promise of the Christ-Age in Recent Literature. William Eugene Mosher [PDF]
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Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Although sex determination is a fundamental process in vertebrate development, it is very plastic. Diverse genes became major sex determinants in teleost fishes.
Annekatrin Richter+13 more
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