Results 101 to 110 of about 12,311,713 (381)

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Evidence for the hallmarks of human aging in replicatively aging yeast

Microbial Cell, 2016
Recently, efforts have been made to characterize the hallmarks that accompany and contribute to the phenomenon of aging, as most relevant for humans [1].
Georges E. Janssens, Liesbeth M. Veenhoff   +1 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Trajectories of Normal Cognitive Aging

Psychology and Aging, 2019
Although sensitive detection of pathological cognitive aging requires accurate information about the trajectory of normal cognitive aging, prior research has revealed inconsistent patterns of age-cognition relations with cross-sectional and longitudinal ...
T. Salthouse
semanticscholar   +1 more source

Validity and reliability of the Persian version of the SARC-F questionnaire among Iranian older adults

BMC Geriatrics
Background Sarcopenia is recognized as a geriatric condition marked by a progressive decline in muscle mass and function. The SARC-F questionnaire was developed as a brief, self-reported, and cost-effective tool for screening sarcopenia.
Sanay Toloueinasab, Ahmad Delbari, Marjan Haghi, Vahid Rashedi, Zhale Zandieh   +4 more
doaj   +1 more source

Effects of testosterone and vitamin D on fall risk in pre-frail hypogonadal men: a factorial design RCT

The Journal of Nutrition, Health and Aging
Objective: To test whether transdermal testosterone at a dose of 75 mg per day and/or monthly 24’000 IU Vitamin D reduces the fall risk in pre-frail hypogonadal men aged 65 and older.
Heike A. Bischoff-Ferrari, Melanie Kistler-Fischbacher, Stephanie Gaengler, Thomas Münzer, Bess Dawson-Hughes, Wei Lang, Robert Theiler, Andreas Egli, E. John Orav, Gregor Freystaetter   +9 more
doaj   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Detection of extracellular amyloid beta aggregates by an Aducanumab-based synNotch receptor: an in vitro proof-of-concept study

Journal of Translational Medicine
Background Synthetic Notch (synNotch) receptors are a powerful gene regulation platform that activate transcription in response to membrane-bound ligands and extracellular matrix components, with emerging applications in cancer, autoimmunity, and ...
Nicholas J. Bergo, Suckwon Lee, Cynthia J. Siebrand, Zachary Mayeri, Julie K. Andersen, Chaska C. Walton   +5 more
doaj   +1 more source

Single Molecule Analysis of Laser Localized Interstrand Crosslinks

Frontiers in Genetics, 2016
DNA interstrand crosslinks (ICLs) block unwinding of the double helix, and have always been regarded as major challenges to replication and transcription. Compounds that form these lesions are very toxic and are frequently used in cancer chemotherapy. We
Jing eHuang, Himabindu eGali, Manikandan eParamasivam, Parameswary eMuniandy, Julia eGichimu, Marina Andrea Bellani, Michael M Seidman   +6 more
doaj   +1 more source

Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span

, 2021
Myriam Grunewald, Saran Kumar, Husni Sharife, E. Volinsky, Alex Gileles‐Hillel, Tamar Licht, Anna Permyakova, Liad Hinden, Shahar Azar, Yasmin Friedmann, P. Kupetz, R. Tzuberi, Andrey Anisimov, Kari Alitalo, M. J. Horwitz, Shira Leebhoff, Oleksiy-Zakhar Khoma, Ruslan Hlushchuk, Valentin Djonov, Rinat Abramovitch, Joseph Tam, Eli Keshet   +21 more
openalex   +2 more sources