Results 221 to 230 of about 12,311,713 (381)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Hevin Promotes Aging-Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice. [PDF]

Aging Cell
Huang SY, Chen YJ, Hu YX, Liu JC, Hu M.
europepmc   +1 more source

Local Abundance of Macular Xanthophyll Pigment Is Associated with Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration [PDF]

, 2020
Deepayan Kar, Mark E. Clark, Thomas A. Swain, Gerald McGwin, Jason N. Crosson, Cynthia Owsley, Kenneth R. Sloan, Christine A. Curcio   +7 more
openalex   +1 more source

Ageing through the Ages

Journal of the Royal College of Physicians of Edinburgh, 1999
MacLennan, W. J., Sellers, W. I.
openaire   +3 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions. [PDF]

Aging Cell
Miyawaki M, Hashimoto S, Ogawa S, Kase Y.   +3 more
europepmc   +1 more source

Diverse impacts of aging on insulin resistance in lean and obese women with polycystic ovary syndrome: evidence from 1345 women with the syndrome [PDF]

, 2014
Sarantis Livadas, Αναστάσιος Κόλλιας, Dimitrios Panidis, Evanthia Diamanti‐Kandarakis   +3 more
openalex   +1 more source

Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP–mediated feedforward loop

, 2021
Yujin Lee, Yoonji Jung, Dae‐Eun Jeong, Wooseon Hwang, Seokjin Ham, Hae‐Eun H. Park, Sujeong Kwon, Jasmine M. Ashraf, Coleen T. Murphy, Seung‐Jae Lee   +9 more
openalex   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

NMNAT1 Activates Autophagy to Delay D-Galactose-Induced Aging in Cochlear Hair Cells. [PDF]

Aging Cell
Wei Y, Yang W, Wu H, Kong M, Fan D, Zhang Y, Cheng N, Du J, Guo L, Li Y, Zhang Y, Dai Q, Cao W, Yang J, Fang Q.   +14 more
europepmc   +1 more source