Results 241 to 250 of about 2,842,411 (305)

SIRT1 deficiency promotes age-related heart failure through enhancing ferroptosis via GATA4-HADHA-GPX4 axis. [PDF]

Cell Death Dis
Duan Y, Luo Y, Han X, Yu H, Liu H, Zhou Y, Gao Y, Xu Q, Wei Y, Min R, Hong Y, Ji X, Jia H, Li Y, Zhang Y.   +14 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Transcriptomic advances in studies of muscle stem cell aging: From bulk to single-cell and beyond. [PDF]

Cell Res
Kim S, Pack SP, Rando TA.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Physiological Effects of Natural and Artificial Aging of Desert Short-Lived Forage Species and Restoration by Gibberellic Acid Priming. [PDF]

Plants (Basel)
Zhao J, Ding Y, Anwar S, Anwar S, Zhao X, Zhou M, Sun Z, He H.   +7 more
europepmc   +1 more source

Perceptions on healthy aging: insights from focus group interviews of older adults in Sweden. [PDF]

Arch Public Health
Frisendahl N, Liljas A, Kirvalidze M, Agerholm J, Welmer AK, Calderón-Larrañaga A.   +5 more
europepmc   +1 more source

Tracking DNA methylation-based biological age over 8 years and its association with mortality in community-dwelling older adults. [PDF]

Clin Epigenetics
Yin Q, Schöttker B, Holleczek B, Fan Z, Stevenson-Hoare J, Brenner H.   +5 more
europepmc   +1 more source

Systematic Druggable Genome-Wide Analysis Identifies Therapeutic Targets for Aging: A Mendelian Randomization Study. [PDF]

Health Sci Rep
Zhang Y, Wang M, Li H, Jin T, Peng S, Dong Y, Deng C, Li H, Li X, Qin J, Ye X.   +10 more
europepmc   +1 more source

Therapeutic peptides in gerontology: mechanisms and applications for healthy aging. [PDF]

Front Aging
Mavrych V, Shypilova I, Bolgova O.
europepmc   +1 more source