Results 221 to 230 of about 2,842,411 (305)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

"De Senectute" in the perioperative and critical care continuum-advancing personalized care for the geriatric patient at the intersection of frailty, aging, and multimorbidity. [PDF]

J Anesth Analg Crit Care
D'Andria Ursoleo J, Bignami EG.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

"Steak Dry Aging": An Innovative Approach to Producing High-Yield, High-Quality Dry-Aged Beef. [PDF]

J Food Sci
Dos Santos JC, Guimarães AS, Bueno LO, Carmo LRD, da Silveira MCT, Ramos ALS, Lopes LS, Ramos EM.   +7 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Evidence-based interventions for promoting healthy aging: a scoping review. [PDF]

J Nutr Health Aging
González-Ballesteros LM, Mojica LE, Riveros S, Zamora VV, Gómez A, Otero Rueda MDP, Chaves Matiz F, Jaimes Velásquez MA, López V, Ramírez L, Sánchez Herrera V.   +10 more
europepmc   +1 more source

Ages of Ages

Ages of Ages is for SATB a capella choir. It is inspired by text taken from the medieval Old Hispanic chant, León 8, fol. 273: Et non deficiet ex te vir qui compleat voluntatem meam; and León 8, fol. 88v: Gloria et honor patri et filio et spiritui sancto et nunc and semper et in saecula saeculorum. An English translation is used for this piece.
openaire   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Psilocybin and human longevity. [PDF]

NPJ Aging
Lerer L.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source