Results 251 to 260 of about 4,011,650 (333)

Association between blood-derived biological aging and bone mineral density among US adults. [PDF]

BMC Musculoskelet Disord
Wu L, Wang J, Liu X, Wang X, Yue X.
europepmc   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Long-term exposure to ambient PM₁ accelerates biological aging in middle-aged and older adults in China. [PDF]

Sci Rep
Ke J, Li S, Cao J, Wang Y, Li S, Qiu F, Zhao F, Cheng X.   +7 more
europepmc   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Gene expression composite scores of cellular senescence predict aging health outcomes in the Health and Retirement Study. [PDF]

Nat Commun
Wu Q, Klopack ET, Kim JK, Arpawong TE, Thyagarajan B, Cole S, Faul JD, Zhou F, Crimmins EM.   +8 more
europepmc   +1 more source

Aging science comes of age [PDF]

npj Aging and Mechanisms of Disease, 2015
openaire   +3 more sources

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

No winners or losers: clinical chemistry-based biological aging metrics perform similarly across cohorts and health outcomes. [PDF]

J Gerontol A Biol Sci Med Sci
Provost G, Tanner K, Legault V, Ferrucci L, Bandinelli S, Fried LP, Belsky DW, Laurent B, Cohen AA.   +8 more
europepmc   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Do single people age faster? The answer may lie in sleep. [PDF]

Front Aging
Chuang JY.
europepmc   +1 more source