Results 251 to 260 of about 12,311,713 (381)

Is the association between psychological distress and risky alcohol consumption shifting over time? An age-period-cohort analysis of the Australian population

, 2023
Jillian Halladay, Tim Slade, Cath Chapman, Louise Mewton, Siobhan O’Dean, Rachel Visontay, Andrew Baillie, Maree Teesson, Matthew Sunderland   +8 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Single-cell transcriptomic profiling of the aging mouse brain

Nature Neuroscience, 2019
Methodios Ximerakis, S. Lipnick, Brendan T. Innes, Sean K. Simmons, Xian Adiconis, Danielle Dionne, Brittany A. Mayweather, Lan Nguyen, Zachary Niziolek, Ceren Ozek, Vincent L. Butty, Ruth Isserlin, Sean M. Buchanan, S. Levine, A. Regev, Gary D Bader, J. Levin, L. Rubin   +17 more
semanticscholar   +1 more source

Organ-Specific Regulation of Systemic Aging: Focus on the Brain, Skeletal Muscle, and Gut. [PDF]

Cells
Fu J, Liu C, Shu Y, Jiang Y, Li P, Yao K.   +5 more
europepmc   +1 more source

The Interrelationship of Tinnitus and Hearing Loss Secondary to Age, Noise Exposure, and Traumatic Brain Injury

, 2022
Royce E. Clifford, Allen F. Ryan, on behalf of VA Million Veteran Program   +2 more
openalex   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Yeast <i>Saccharomyces cerevisiae</i> as a Model to Study the Anti-Aging Activity of Phycocyanin. [PDF]

Int J Mol Sci
Cassamagnaghi D, Citterio S, Martegani E, Colombo S.   +3 more
europepmc   +1 more source

Age Integration or Age Conflict as Society Ages? [PDF]

The Gerontologist, 2000
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Prediction of Targets and Mechanisms of Top Ten Core "Food-Medicine Homologous Traditional Chinese Medicines" in Delaying Vascular Aging: An Integrative Computational Study. [PDF]

Pharmaceuticals (Basel)
Bai Y, Liu Q, Zhou Q, Xiao P, Xia L.
europepmc   +1 more source