Results 41 to 50 of about 4,068,492 (287)

Bridging the divide: supporting and mentoring trainees to conceptualize, plan, and integrate engagement of people with lived experience in health research

Research Involvement and Engagement
Health researchers are encouraged by governments, funders, and journals to conduct research in partnership with people with lived experience. However, conducting research with authentic engagement and partnership with those who are experts by experience,
Soo Chan Carusone, Cassandra D’Amore, Subhash Dighe, Lance Dingman, A. Tina Falbo, Michael Kirk, Joyce Luyckx, Mark McNeil, Kim Nolan, Penelope Petrie, Donna Weldon, Rebecca Ganann, Brenda Vrkljan   +12 more
doaj   +1 more source

Aging, rejuvenation and thixotropy in complex fluids. Time-dependence of the viscosity at rest and under constant shear rate or shear stress [PDF]

, 2008
Complex fluids exhibit time-dependent changes in viscosity that have been ascribed to both thixotropy and aging. However, there is no consensus for which phenomenon is the origin of which changes.
Quemada, Daniel
core   +4 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

The Prevention Research Centers Healthy Aging Research Network

Preventing Chronic Disease, 2005
BackgroundThe Prevention Research Centers Healthy Aging Research Network (PRC–HAN), funded by the Centers for Disease Control and Prevention’s (CDC’s) Healthy Aging program, was created in 2001 to help develop partnerships and create a research agenda ...
The Healthy Aging Research Network Writing Group
doaj  

ActRII or BMPR ligands inhibit skeletal myoblast differentiation, and BMPs promote heterotopic ossification in skeletal muscles in mice

Skeletal Muscle
Background Prior studies suggested that canonical Activin Receptor II (ActRII) and BMP receptor (BMPR) ligands can have opposing, distinct effects on skeletal muscle depending in part on differential downstream SMAD activation.
Marc A. Egerman, Yuhong Zhang, Romain Donne, Jianing Xu, Abhilash Gadi, Corissa McEwen, Hunter Salmon, Kun Xiong, Yu Bai, Mary Germino, Kevin Barringer, Yasalp Jimenez, Maria del Pilar Molina-Portela, Tea Shavlakadze, David J. Glass   +14 more
doaj   +1 more source

Inhibition of MAT2A Impairs Skeletal Muscle Repair Function

Biomolecules
The regenerative capacity of muscle, which primarily relies on anabolic processes, diminishes with age, thereby reducing the effectiveness of therapeutic interventions aimed at treating age-related muscle atrophy.
Wanli Xiao, Tian-E Huang, Jing Zhou, Benhui Wang, Xiang Wang, Weirong Zeng, Qiquan Wang, Xinqiang Lan, Yang Xiang   +8 more
doaj   +1 more source

Aging in humid granular media

, 2002
Aging behavior is an important effect in the friction properties of solid surfaces. In this paper we investigate the temporal evolution of the static properties of a granular medium by studying the aging over time of the maximum stability angle of ...
A. Forsyth, A.L. Barabasi, Cécile Ursini, D. Hornbaker, E. Nowak, F. Heslot, F. Restagno, Frédéric Restagno, G. D’Anna, G. Ovarlez, H. Christenson, H. Jaeger, Hervé Gayvallet, J. Crassous, J. Crassous, J. Dieterich, J.-C. Geminard, L. Bocquet, M. Kohonen, M. Lubert, N. Fraysse, P. Tegzes, P.-G. De Gennes, R. Albert, S. Nasuno, S. Nasuno, T. Baumberger, T.C. Halsey, T.G. Mason, Y. Grasselli, Élisabeth Charlaix   +30 more
core   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

The Effect of an Aging Suit on Young and Middle-Aged Adults’ Attitudes Toward Older Adults [PDF]

, 2018
Background: Ageism, a type of discrimination based on a person’s age, can lead to negative attitudes, intolerance, and judgment towards older adults. With the increase of older adults in society, understanding the correlates of negative attitudes becomes
Allen, Kelly
core   +2 more sources