Results 81 to 90 of about 4,068,492 (287)
Association of cesarean birth with prevalence of functional constipation in toddlers at 3 years of age: results from the Japan Environment and Children’s Study (JECS) [PDF]
, 2021 Mari Nakamura, Kenta Matsumura, Yoshiko Ohnuma, Taketoshi Yoshida, Akiko Tsuchida, Kei Hamazaki, Hidekuni Inadera, Michihiro Kamijima, Shin Yamazaki, Yukihiro Ohya, Reiko Kishi, Nobuo Yaegashi, Koichi Hashimoto, Chisato Mori, Shuichi Ito, Zentaro Yamagata, Hidekuni Inadera, Takeo Nakayama, Hiroyasu Iso, Masayuki Shima, Youichi Kurozawa, Narufumi Suganuma, Koichi Kusuhara, Takahiko Katoh +23 moreopenalex +1 more sourceChemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam +14 morewiley +1 more sourceThe WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine
Nature Communications, 2019 Notch signaling mediates intestinal enteroblast specification in Drosophila but the molecular mechanism as to how this is regulated is unclear. Here, the authors show that the transcription factor Klumpfuss ensures enteroblast commitment through ...Jerome Korzelius, Sina Azami, Tal Ronnen-Oron, Philipp Koch, Maik Baldauf, Elke Meier, Imilce A. Rodriguez-Fernandez, Marco Groth, Pedro Sousa-Victor, Heinrich Jasper +9 moredoaj +1 more sourceTonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes +17 morewiley +1 more sourceHandelin alleviates cachexia‐ and aging‐induced skeletal muscle atrophy by improving protein homeostasis and inhibiting inflammation
Journal of Cachexia, Sarcopenia and MuscleBackground Handelin is a bioactive compound from Chrysanthemum indicum L. that improves motor function and muscle integrity during aging in Caenorhabditis elegans.Hui‐Jie Zhang, Ben‐Hui Wang, Xiang Wang, Chun‐Ping Huang, Si‐Man Xu, Jia‐Li Wang, Tian‐E Huang, Wan‐Li Xiao, Xiao‐Li Tian, Xin‐Qiang Lan, Qi‐Quan Wang, Yang Xiang +11 moredoaj +1 more sourceAging Logarithmic Conformal Field Theory : a holographic view
, 2012 We consider logarithmic extensions of the correlation and response functions
of scalar operators for the systems with aging as well as Schr\"odinger
symmetry.A Adams, A Ghezelbash, AL Barabási, Bom Soo Kim, BS Kim, BS Kim, BS Kim, CP Herzog, D Grumiller, D Grumiller, D Grumiller, D Son, D Yamada, DT Son, EA Bergshoeff, EA Bergshoeff, EA Bergshoeff, EG Gimon, F Family, H Hinrichsen, H Lü, H Lü, II Kogan, J Maldacena, Jaehoon Jeong, JI Jottar, JL Barbon, K Balasubramanian, K Skenderis, KA Takeuchi, KA Takeuchi, M Alishahiha, M Alishahiha, M Alishahiha, M Ammon, M Flohr, M Henkel, M Henkel, M Henkel, M Henkel, M Henkel, M Henneaux, M Kardar, M Porrati, MR Gaberdiel, N Johansson, O Aharony, S Deser, S Hyun, S Hyun, S-J Hyun, Seungjoon Hyun, SF Edwards, WD Goldberger, Y Nakayama, YS Myung +55 morecore +1 more sourceInfluenza-Associated Excess Mortality by Age, Sex, and Subtype/Lineage: Population-Based Time-Series Study With a Distributed-Lag Nonlinear Model [PDF]
, 2022 Li Li, Ze-Lin Yan, Lei Luo, Wenhui Liu, Yang Zhou, Chen Shi, Bo-Wen Ming, Jun Yang, Peihua Cao, Chun‐Quan Ou +9 moreopenalex +1 more sourceDetecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda +12 morewiley +1 more sourceEstimated age of first exposure to American football and outcome from concussion [PDF]
, 2020 Jaclyn B. Caccese, Zac Houck, Thomas W. Kaminski, James R. Clugston, Grant L. Iverson, Kelsey Bryk, Jessie R. Oldham, Paul F. Pasquina, Steven P. Broglio, Thomas W. McAllister, Michael McCrea, April Marie Hoy, Joseph B. Hazzard, Louise A. Kelly, Justus D. Ortega, Nicholas Port, Margot Putukian, Theresa Dianne Langford, Christopher C. Giza, Joshua Goldman, Holly J. Benjamin, Julianne D. Schmidt, Luis A. Feigenbaum, James T. Eckner, Jason P. Mihalik, Jessica Dysart Miles, Scott A. Anderson, Christina L. Master, Micky Collins, Anthony P. Kontos, Sara P. D. Chrisman, Alison Brooks, Jonathan C. Jackson, Gerald McGinty, Kenneth L. Cameron, Adam Susmarski, Patrick O’Donnell, Stefan M. Duma, Steven Rowson, Christopher M. Miles, Christopher Todd Bullers, Brian H. Dykhuizen, Laura Lintner, Thomas A. Buckley +43 moreopenalex +1 more source
