Results 101 to 110 of about 1,760,131 (304)

[Coalition for Aging LGBT Nametag Lanyard]

Photograph from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
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Aging in place begins in the bathroom

, 2012
Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.

core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Denervation alters the secretome of myofibers and thereby affects muscle stem cell lineage progression and functionality

npj Regenerative Medicine
Skeletal muscle function crucially depends on innervation while repair of skeletal muscle relies on resident muscle stem cells (MuSCs). However, it is poorly understood how innervation affects MuSC properties and thereby regeneration of skeletal muscle ...
Henriette Henze, Sören S. Hüttner, Philipp Koch, Svenja C. Schüler, Marco Groth, Björn von Eyss, Julia von Maltzahn   +6 more
doaj   +1 more source

Quantitative mapping of proteasome interactomes and substrates using ProteasomeID

eLife
Proteasomes are essential molecular machines responsible for the degradation of proteins in eukaryotic cells. Altered proteasome activity has been linked to neurodegeneration, auto-immune disorders and cancer.
Aleksandar Bartolome, Julia C Heiby, Domenico Di Fraia, Ivonne Heinze, Hannah Knaudt, Ellen Spaeth, Omid Omrani, Alberto Minetti, Maleen Hofmann, Joanna M Kirkpatrick, Therese Dau, Alessandro Ori   +11 more
doaj   +1 more source

Vision care - like aging - is everybody's business

, 2012
Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.
Davis, Jackie
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Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Preliminary effects of a four-month circuit training intervention on cognitive function and exploratory plasma proteomic profiles in middle-aged and older women: an open-label randomized controlled trial

Frontiers in Sports and Active Living
BackgroundAlthough exercise can help prevent age-related cognitive decline, the mechanisms underlying its effects on cognition, immune function remain unclear.
Keishi Soga, Michio Takahashi, Michio Takahashi, Kentaro Oba, Akari Uno, Akari Uno, Akari Uno, Takuji Kawamura, Keisei Kawashima, Takamitsu Shinada, Yasuyuki Taki, Yasuyuki Taki   +11 more
doaj   +1 more source

[Photograph of Officers of the Coalition for Aging LGBT]

Color photograph of Officers of the Coalition for Aging LGBT and offices of The Dallas Way at the 2023 Legacy Dinner for Lambda Legal from the Coalition for Aging LGBT Records (The Dallas Way)
Colaition for Aging LGBT
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Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source