Results 61 to 70 of about 12,999,964 (309)

Single Molecule Analysis of Laser Localized Interstrand Crosslinks

open access: yesFrontiers in Genetics, 2016
DNA interstrand crosslinks (ICLs) block unwinding of the double helix, and have always been regarded as major challenges to replication and transcription. Compounds that form these lesions are very toxic and are frequently used in cancer chemotherapy. We
Jing eHuang   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

[Coalition for Aging LGBT Pamphlet]

open access: yes
Pamphlet from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
core   +1 more source

O papel da odontologia na equipe interdisciplinar: contribuindo para a atenção integral ao idoso

open access: yesCadernos de Saúde Pública
Este trabalho bibliográfico teve por objetivo discutir a atuação da odontologia na atenção integral à saúde do idoso, considerando-se a necessidade da abordagem interdisciplinar. É apresentada a atual situação da odontologia geriátrica e os problemas que
Rosemary Sadami Arai Shinkai   +1 more
doaj  

Pancreas++ : Automated Quantification of Pancreatic Islet Cells in Microscopy Images

open access: yesFrontiers in Physiology, 2013
The microscopic image analysis of pancreatic Islet of Langerhans morphology is crucial for the investigation of diabetes and metabolic diseases. Besides the general size of the islet, the percentage and relative position of glucagon-containing alpha ...
Hongyu eChen   +6 more
doaj   +1 more source

Other title: Kansas State Advisory Council on Aging report for fiscal years--Other title: Kansas Advisory Council on Aging annual report

open access: yes, 1979
The reports were prepared with the assistance of the Kansas Department on Aging.; Created in 1977 by the Kansas Act on the Aging, the ACA is represents different geographical, social and ethnic groups, with at least half its members being 60 years of age
Kansas Advisory Council on Aging.
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The Neuromuscular Junction (NMJ): aging at the crossroad between nerves and muscle

open access: yesFrontiers in Aging Neuroscience, 2014
Aging is associated with a progressive loss of muscle mass and strength and a decline in neurophysiological functions. Age-related neuromuscular junction (NMJ) plays a key role in musculoskeletal impairment that occurs with aging.
Marta eGonzalez-Freire   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Two-year follow-up study of elderly residents in S. Paulo, Brazil: methodology and preliminary results

open access: yesRevista de Saúde Pública
INTRODUCTION: Previous cross-sectional studies have shown a high prevalence of chronic disease and disability among the elderly. Given Brazil’s rapid aging process and the obvious consequences of the growing number of old people with chronic diseases and
Luiz R. Ramos   +19 more
doaj  

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