COVID-19 and chronological aging : senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection? [PDF]
, 2020 COVID-19, also known as SARS-CoV-2, is a new emerging zoonotic corona virus of the SARS (Severe Acute Respiratory Syndrome) and the MERS (Middle East Respiratory Syndrome) family.
Auwerx +30 more
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Journal of Lipid Research, 2003 We examined the effect of etomoxir treatment on de novo cardiolipin (CL) biosynthesis in H9c2 cardiac myoblast cells. Etomoxir treatment did not affect the activities of the CL biosynthetic and remodeling enzymes but caused a reduction in [1-14C]palmitic
Fred Y. Xu +3 more
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Childhood asthma diagnoses declined during the COVID-19 pandemic in the United States
Respiratory Research, 2023 Background Prior studies have documented declines in pediatric asthma exacerbations and asthma-related health care utilization during the COVID-19 pandemic, but less is known about the incidence of asthma during the pandemic.
Daniel B. Horton +7 more
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The Effect of Heat Treatment on the Microstructure Evolution and Properties of an Age-Hardened Cu-3Ti-2Mg Alloy [PDF]
Archives of Metallurgy and Materials, 2020 The study investigates the effect of heat treatment on the microstructure evolution and properties of an age-hardened Cu-3Ti-2Mg alloy. The precipitated Cu2Mg and β'-Cu4Ti phases consequently yield a depletion of the Cu matrix in regards to Ti and Mg ...
Jituo Liu +3 more
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Effect of composition and heat treatment on the mechanical properties of Fe Mn Al steels
Fracture and Structural Integrity, 2022 Starting from the research aimed at the development of substitute alloys for stainless steels, with the aim of replacing strategic metals such as chromium and nickel with the more available manganese, FeMnAlC alloys have been studied and developed for ...
A. Mondal +3 more
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Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly [PDF]
, 2017 Significance: The incidence of cardiovascular events (CVEs) increases with age, representing the main cause of death in an elderly population. Aging is associated with overproduction of reactive oxygen species (ROS), which may affect clotting and ...
Carnevale, Roberto +4 more
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A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells. [PDF]
, 2015 Aging is characterized by a progressive deterioration in physiological functions and metabolic processes. The loss of cells during aging in vital tissues and organs is related to several factors including oxidative stress and inflammation.
Borsani, Elisa +7 more
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Xi'an Gongcheng Daxue xuebao, 2022 In order to improve the comprehensive properties of copper matrix composites, the supersaturated Cu-Ti alloy powder mixed with titanium carbide was prepared by mechanical alloying method. After the prepared powder pressed and sintered, the TiC reinforced
WANG Yanlong, LIU Chen, GAO Zeyu
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Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]
, 2016 Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V +7 more
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Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice [PDF]
, 2016 The FDA approved drug rapamycin increases lifespan in rodents and delays age-related dysfunction in rodents and humans. Nevertheless, important questions remain regarding the optimal dose, duration, and mechanisms of action in the context of healthy ...
Anderson +33 more
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